Literature DB >> 18375562

Sodium chloride affects Helicobacter pylori growth and gene expression.

Hanan Gancz1, Kathleen R Jones, D Scott Merrell.   

Abstract

Epidemiological evidence links high-salt diets and Helicobacter pylori infection with increased risk of developing gastric maladies. The mechanism by which elevated sodium chloride content causes these manifestations is unclear. Here we characterize the response of H. pylori to temporal changes in sodium chloride concentration and show that growth, cell morphology, survival, and virulence factor expression are all altered by increased salt concentration.

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Year:  2008        PMID: 18375562      PMCID: PMC2395038          DOI: 10.1128/JB.01728-07

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  33 in total

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  33 in total

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7.  High-Salt Conditions Alter Transcription of Helicobacter pylori Genes Encoding Outer Membrane Proteins.

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Review 8.  Clinical proteomics identifies potential biomarkers in Helicobacter pylori for gastrointestinal diseases.

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9.  Dietary Composition Influences Incidence of Helicobacter pylori-Induced Iron Deficiency Anemia and Gastric Ulceration.

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