Literature DB >> 1837534

Regional localization of the hepatocyte growth factor (HGF) gene to human chromosome 7 band q21.1.

R Fukuyama1, Y Ichijoh, S Minoshima, N Kitamura, N Shimizu.   

Abstract

Hepatocyte growth factor (HGF) is a polypeptide involved in liver regeneration. Its amino acid sequence and gene structure are similar to those of coagulation-related serine proteases. We have used a cDNA clone of HGF and flow-sorted human chromosomes to assign this gene to chromosome 7. Fluorescence in situ hybridization of the HGF genomic clones to human metaphase chromosome spreads showed the localization of this gene to 7q21. Estimation of fluorescent signals relative to arbitrary reference points (ARPs) allowed further localization to 7q21.1.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1837534     DOI： 10.1016/0888-7543(91)90149-9

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  8 in total

1.  Chromosomal localization of rat hepatocyte growth factor (Hgf) and HGF receptor (Met) and characterization of HGF receptor cDNA.

Authors:  V R Wallenius; H Rawet; S Skrtic; K Helou; Y Qiu; G Levan; S Ekberg; B Carlsson; O G Isaksson; T Nakamura; J O Jansson
Journal:  Mamm Genome       Date:  1997-09       Impact factor: 2.957

Review 2.  Mechanisms of HGF/Met signaling to Brk and Sam68 in breast cancer progression.

Authors:  Alessia Locatelli; Kristopher A Lofgren; Andrea R Daniel; Nancy E Castro; Carol A Lange
Journal:  Horm Cancer       Date:  2012-04       Impact factor: 3.869

3.  Biological roles of hepatocyte growth factor-Met signaling from genetically modified animals.

Authors:  Takashi Kato
Journal:  Biomed Rep       Date:  2017-10-18

4.  Expression of HGF mRNA in human rejecting kidney as evidenced by in situ hybridization.

Authors:  K Yamaguchi; M A Nalesnik; G K Michalopoulos
Journal:  Urol Res       Date:  1996

5.  Precise mapping of the EGF receptor gene on the human chromosome 7p12 using an improved fish technique.

Authors:  Y Wang; S Minoshima; N Shimizu
Journal:  Jpn J Hum Genet       Date:  1993-12

Review 6.  Fine mapping of the autosomal dominant split hand/split foot locus on chromosome 7, band q21.3-q22.1.

Authors:  S W Scherer; P Poorkaj; T Allen; J Kim; D Geshuri; M Nunes; S Soder; K Stephens; R A Pagon; M A Patton
Journal:  Am J Hum Genet       Date:  1994-07       Impact factor: 11.025

7.  Transforming growth factor-β1 selectively inhibits hepatocyte growth factor expression via a micro-RNA-199-dependent posttranscriptional mechanism.

Authors:  Ognoon Mungunsukh; Regina M Day
Journal:  Mol Biol Cell       Date:  2013-05-08       Impact factor: 4.138

8.  Detection of epidermal growth factor receptor gene amplification in human squamous cell carcinomas using fluorescence in situ hybridization.

Authors:  N Shimizu; Y Wang; S Minoshima; J Ishitoya
Journal:  Jpn J Cancer Res       Date:  1994-06
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.