Literature DB >> 18375184

Asymptomatic uterine fibroids.

Hema Divakar1.   

Abstract

It is estimated that at least 50% of fibroids are asymptomatic, but this figure is likely to be an underestimate as it is based on women in whom fibroids are found incidentally during another procedure (e.g. cervical screening), and there is little, if any, data from population studies on the true incidence of fibroids. If a prevalence of 50% by 50 years of age is accepted, a large number of women have asymptomatic fibroids. Working on the cliché, 'if it ain't broken, don't fix it', it may seem surprising that there should be a chapter dedicated to the issue of asymptomatic fibroids, since the simplistic approach might be to leave the asymptomatic fibroids well alone. However, asymptomatic fibroids may become symptomatic in the future, so it may be wiser to treat fibroids before they grow to a size when they become symptomatic, or treatment becomes more challenging, especially in young women who may desire fertility at a later stage, and in view of the fact that many women are starting their families in their mid-thirties when they have a 30% chance of having a fibroid(s). Despite their common occurrence, fibroids are still poorly understood. It is not known why they form in the first place, what determines their number and ultimate size, the best treatment approaches, or the factors that determine which women develop symptoms. Even when women present with disorders such as infertility, pelvic pain and abnormal bleeding, it is not always possible to be certain that a given myoma is not simply an innocent bystander rather than the cause of the symptom. This chapter addresses the challenging issue of what to do when fibroids are diagnosed incidentally. Firstly, there is the need to ascertain that the pelvic mass palpated is indeed a fibroid, and not an early, more sinister tumour, especially if conservative management is adopted. In addition, there is the issue of size, position and potential for becoming symptomatic at a later date. With the availability of uterine-preserving and largely non-invasive treatment modalities, should more asymptomatic, younger women be offered treatment if it is deemed that their fibroids may cause problems as they grow? Where treatment is not offered, is it necessary to follow-up such women, and if so, with what modality of surveillance and how frequently?

Entities:  

Mesh:

Year:  2008        PMID: 18375184     DOI: 10.1016/j.bpobgyn.2008.01.007

Source DB:  PubMed          Journal:  Best Pract Res Clin Obstet Gynaecol        ISSN: 1521-6934            Impact factor:   5.237


  16 in total

Review 1.  Updates on MR-Guided Focused Ultrasound for Symptomatic Uterine Fibroids.

Authors:  Divya Sridhar; Maureen P Kohi
Journal:  Semin Intervent Radiol       Date:  2018-04-05       Impact factor: 1.513

2.  Incarceration of a pedunculated uterine fibroid in an umbilical hernia.

Authors:  Mi Ju Kim; Hyun-Hwa Cha; Won Joon Seong
Journal:  Obstet Gynecol Sci       Date:  2017-05-15

Review 3.  Circulating Transcripts and Biomarkers in Uterine Tumors: Is There a Predictive Role?

Authors:  Christine De Bruyn; Thaïs Baert; Thierry Van den Bosch; An Coosemans
Journal:  Curr Oncol Rep       Date:  2020-01-29       Impact factor: 5.075

4.  Fears and Concerns of Patients with Uterine Fibroids - a Survey of 807 Women.

Authors:  Nina Isabelle Knudsen; Klaus-D Wernecke; Friederike Siedentopf; Matthias David
Journal:  Geburtshilfe Frauenheilkd       Date:  2017-09-25       Impact factor: 2.915

5.  A single baseline ultrasound assessment of fibroid presence and size is strongly predictive of future uterine procedure: 8-year follow-up of randomly sampled premenopausal women aged 35-49 years.

Authors:  D D Baird; T M Saldana; D L Shore; M C Hill; J M Schectman
Journal:  Hum Reprod       Date:  2015-09-25       Impact factor: 6.918

6.  Recurrence after robotic myomectomy: is it associated with use of GnRH agonist?

Authors:  Roopina Sangha; Vivek Katukuri; Matthew Palmer; Raminder Kaur Khangura
Journal:  J Robot Surg       Date:  2016-04-12

7.  Effects of obesity and hormone therapy on surgically-confirmed fibroids in postmenopausal women.

Authors:  Eva M Sommer; Angela Balkwill; Gillian Reeves; Jane Green; Dame Valerie Beral; Kate Coffey
Journal:  Eur J Epidemiol       Date:  2015-03-18       Impact factor: 8.082

Review 8.  Pharmacological treatment of uterine fibroids.

Authors:  Rm Moroni; Cs Vieira; Ra Ferriani; Fj Candido-Dos-Reis; Lgo Brito
Journal:  Ann Med Health Sci Res       Date:  2014-09

Review 9.  Presentation and treatment of uterine leiomyoma in adolescence: a systematic review.

Authors:  Rafael Mendes Moroni; Carolina Sales Vieira; Rui Alberto Ferriani; Rosana Maria dos Reis; Antonio Alberto Nogueira; Luiz Gustavo Oliveira Brito
Journal:  BMC Womens Health       Date:  2015-01-22       Impact factor: 2.809

10.  In-bag manual versus uncontained power morcellation for laparoscopic myomectomy.

Authors:  Fulvio Zullo; Roberta Venturella; Antonio Raffone; Gabriele Saccone
Journal:  Cochrane Database Syst Rev       Date:  2020-05-06
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.