BACKGROUND: The objective of this study is to test Davidson's, and Heller and Nitschke's models stating cortical activity in adolescents to be a marker for increased risk for depression. METHODS: Alpha activity was measured in 80 adolescents from medial-frontal (F3/4), lateral-frontal (F7/8), and medial-parietal (P3/4) electrodes, as well as self-reported depression and anxiety twice within 12 months. Step-wise hierarchical regression analyses with anxiety as covariate were calculated with alpha asymmetry as predicting variable and depression as target variable and vice versa. RESULTS: Independent of whether anxiety was used as covariate or not, frontal and parietal alpha asymmetry predict depression, but depression did not predict alpha activity. CONCLUSIONS: The results partially support both models and conclusions drawn by studies with remitted depressed subjects. However, it remains unclear if anxious arousal has a partial influence on the predictive association between alpha activity and depression.
BACKGROUND: The objective of this study is to test Davidson's, and Heller and Nitschke's models stating cortical activity in adolescents to be a marker for increased risk for depression. METHODS: Alpha activity was measured in 80 adolescents from medial-frontal (F3/4), lateral-frontal (F7/8), and medial-parietal (P3/4) electrodes, as well as self-reported depression and anxiety twice within 12 months. Step-wise hierarchical regression analyses with anxiety as covariate were calculated with alpha asymmetry as predicting variable and depression as target variable and vice versa. RESULTS: Independent of whether anxiety was used as covariate or not, frontal and parietal alpha asymmetry predict depression, but depression did not predict alpha activity. CONCLUSIONS: The results partially support both models and conclusions drawn by studies with remitted depressed subjects. However, it remains unclear if anxious arousal has a partial influence on the predictive association between alpha activity and depression.
Authors: Brittany R Alperin; Christiana J Smith; Hanna C Gustafsson; McKenzie T Figuracion; Sarah L Karalunas Journal: J Psychiatr Res Date: 2019-06-18 Impact factor: 4.791
Authors: Stewart A Shankman; Daniel N Klein; Dana C Torpey; Thomas M Olino; Margaret W Dyson; Jiyon Kim; C Emily Durbin; Brady D Nelson; Craig E Tenke Journal: Dev Psychopathol Date: 2011-05