Literature DB >> 18373120

Early experience with the bioabsorbable anal fistula plug.

D A Lawes1, J E Efron, M Abbas, J Heppell, T M Young-Fadok.   

Abstract

PURPOSE: Management of anal fistula represents a balance between curing the condition and maintaining anal continence. Recent reports of the results of the porcine anal fistula plug have demonstrated excellent fistula healing rates without reporting significant complications.
METHODS: The outcome of patients who underwent treatment for anal fistula with the Surgisis anal plug was retrospectively reviewed.
RESULTS: Twenty patients were treated; three underwent concomitant anal advancement flap at the time of plug placement. Seventeen patients had a trans-sphincteric fistula, and three had an anoperineal fistula. Ten patients had previously undergone failed surgical therapy to cure their fistula, including anal advancement flap in four, muscle interposition flap in two, fistulotomy in two, and cutting seton placement in two. Mean follow-up was 7.4 months. Only 4 of 17 (24%) patients treated with the plug alone had closure of their fistula. Acute postoperative sepsis was seen in 5 of 17 (29%) patients treated with the plug alone. Four developed perianal abscesses that required incision and drainage, and one intersphincteric abscess was treated with antibiotics. Two of the patients who underwent concomitant anal advancement flaps and plug placement healed successfully.
CONCLUSIONS: Contrary to other published series, the use of the Surgisis anal plug was associated with a low rate of fistula healing and a high incidence of perianal sepsis. The addition of a transanal advancement flap to the procedure may improve success rates.

Entities:  

Mesh:

Year:  2008        PMID: 18373120     DOI: 10.1007/s00268-008-9504-1

Source DB:  PubMed          Journal:  World J Surg        ISSN: 0364-2313            Impact factor:   3.352


  16 in total

1.  Outcomes of primary repair of anorectal and rectovaginal fistulas using the endorectal advancement flap.

Authors:  Toyooki Sonoda; Tracy Hull; Marion R Piedmonte; Victor W Fazio
Journal:  Dis Colon Rectum       Date:  2002-12       Impact factor: 4.585

2.  Efficacy of anal fistula plug in closure of Crohn's anorectal fistulas.

Authors:  Lynn O'Connor; Bradley J Champagne; Martha A Ferguson; Guy R Orangio; Marion E Schertzer; David N Armstrong
Journal:  Dis Colon Rectum       Date:  2006-10       Impact factor: 4.585

3.  Fibrin glue as an adjunct to flap repair of anal fistulas: a randomized, controlled study.

Authors:  C Neal Ellis; Stephen Clark
Journal:  Dis Colon Rectum       Date:  2006-11       Impact factor: 4.585

4.  Excision of anal fistula with closure of the internal opening: functional and manometric results.

Authors:  Ulla-Maria Gustafsson; Wilhelm Graf
Journal:  Dis Colon Rectum       Date:  2002-12       Impact factor: 4.585

5.  Endorectal advancement flap repair of rectovaginal and other complicated anorectal fistulas.

Authors:  I J Kodner; A Mazor; E I Shemesh; R D Fry; J W Fleshman; E H Birnbaum
Journal:  Surgery       Date:  1993-10       Impact factor: 3.982

6.  Endorectal flap advancement repair and fistulectomy for high trans-sphincteric and suprasphincteric fistulas.

Authors:  H Ortíz; J Marzo
Journal:  Br J Surg       Date:  2000-12       Impact factor: 6.939

7.  Efficacy of anal fistula plug in closure of cryptoglandular fistulas: long-term follow-up.

Authors:  Bradley J Champagne; Lynn M O'Connor; Martha Ferguson; Guy R Orangio; Marion E Schertzer; David N Armstrong
Journal:  Dis Colon Rectum       Date:  2006-12       Impact factor: 4.585

8.  Efficacy of fibrin sealant in the management of complex anal fistula: a prospective trial.

Authors:  Gordon N Buchanan; Clive I Bartram; Robin K S Phillips; Stuart W T Gould; Steve Halligan; Tim A Rockall; Paul Sibbons; Richard G Cohen
Journal:  Dis Colon Rectum       Date:  2003-09       Impact factor: 4.585

9.  Mucosal advancement in the treatment of anal fistula.

Authors:  P S Aguilar; G Plasencia; T G Hardy; R F Hartmann; W R Stewart
Journal:  Dis Colon Rectum       Date:  1985-07       Impact factor: 4.585

10.  Continence disorders after anal fistulotomy.

Authors:  W F van Tets; H C Kuijpers
Journal:  Dis Colon Rectum       Date:  1994-12       Impact factor: 4.585

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  24 in total

1.  Acellular extracellular matrix anal fistula plug: results in high fistula-in-ano awaited.

Authors:  Pankaj Garg
Journal:  World J Gastroenterol       Date:  2008-12-14       Impact factor: 5.742

2.  Current management of cryptoglandular fistula-in-ano.

Authors:  Joshua I S Bleier; Husein Moloo
Journal:  World J Gastroenterol       Date:  2011-07-28       Impact factor: 5.742

3.  Early experience with the modificated approach of ligation of the intersphincteric fistula tract for high transsphincteric fistula.

Authors:  Feng Ye; Changling Tang; Danyang Wang; Shusen Zheng
Journal:  World J Surg       Date:  2015-04       Impact factor: 3.352

Review 4.  Modern management of anal fistula.

Authors:  Elsa Limura; Pasquale Giordano
Journal:  World J Gastroenterol       Date:  2015-01-07       Impact factor: 5.742

Review 5.  The treatment of anal fistulas with biologically derived products: is innovation better than conventional surgical treatment? An update.

Authors:  Roberto Cirocchi; Stefano Trastulli; Umberto Morelli; Jacopo Desiderio; Carlo Boselli; Amilcare Parisi; Giuseppe Noya
Journal:  Tech Coloproctol       Date:  2012-12-04       Impact factor: 3.781

6.  Results of the Gore Bio-A fistula plug implantation in the treatment of anal fistula: a multicentre study.

Authors:  A Herold; A Ommer; A Fürst; F Pakravan; D Hahnloser; B Strittmatter; T Schiedeck; F Hetzer; F Aigner; E Berg; M Roblick; D Bussen; A Joos; S Vershenya
Journal:  Tech Coloproctol       Date:  2016-07-14       Impact factor: 3.781

7.  Treatment of fistula-in-ano using a porcine small intestinal submucosa anal fistula plug.

Authors:  J R Cintron; H Abcarian; V Chaudhry; M Singer; S Hunt; E Birnbaum; M G Mutch; J Fleshman
Journal:  Tech Coloproctol       Date:  2012-09-28       Impact factor: 3.781

8.  Quality of life with anal fistula.

Authors:  H A Owen; G N Buchanan; A Schizas; R Cohen; A B Williams
Journal:  Ann R Coll Surg Engl       Date:  2016-05       Impact factor: 1.891

Review 9.  Surgery for anal fistulae: state of the art.

Authors:  Mario Pescatori
Journal:  Int J Colorectal Dis       Date:  2021-05-31       Impact factor: 2.571

10.  Ligation of intersphincteric fistula tract and its modification: Results from treatment of complex fistula.

Authors:  Siripong Sirikurnpiboon; Burin Awapittaya; Paiboon Jivapaisarnpong
Journal:  World J Gastrointest Surg       Date:  2013-04-27
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