| Literature DB >> 18371430 |
Abstract
Understanding the development and maintenance of dopamine neurons is essential to establish novel stem cell therapies and animal models of Parkinson's disease. A recent PLoS Biology report (Kittappa et al., 2007) reveals that Foxa2 regulates dopamine neuron generation and differentiation, and that aging foxa2(+/-) mice spontaneously develop Parkinsonism.Entities:
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Year: 2008 PMID: 18371430 DOI: 10.1016/j.stem.2008.01.012
Source DB: PubMed Journal: Cell Stem Cell ISSN: 1875-9777 Impact factor: 24.633