Literature DB >> 18371428

How do mesenchymal stromal cells suppress T cells?

Armand Keating1.   

Abstract

Accumulating information indicates that mesenchymal stem or stromal cells (MSCs) are immunomodulatory, but the data to explain the observations are frequently conflicting. In this issue of Cell Stem Cell, Ren et al. (2008) provide evidence for a possible underlying mechanism of MSC-mediated T cell suppression. A perspective for considering these interesting observations is discussed.

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Year:  2008        PMID: 18371428     DOI: 10.1016/j.stem.2008.01.007

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN: 1875-9777            Impact factor:   24.633


  42 in total

1.  Immune modulation of co-transplantation mesenchymal stem cells with islet on T and dendritic cells.

Authors:  F R Li; X G Wang; C Y Deng; H Qi; L L Ren; H X Zhou
Journal:  Clin Exp Immunol       Date:  2010-05-07       Impact factor: 4.330

Review 2.  Overcoming immunoregulatory plasticity of mesenchymal stem cells for accelerated clinical applications.

Authors:  Nayoun Kim; Seok-Goo Cho
Journal:  Int J Hematol       Date:  2015-12-11       Impact factor: 2.490

3.  A reproducible immunopotency assay to measure mesenchymal stromal cell-mediated T-cell suppression.

Authors:  Debra D Bloom; John M Centanni; Neehar Bhatia; Carol A Emler; Diana Drier; Glen E Leverson; David H McKenna; Adrian P Gee; Robert Lindblad; Derek J Hei; Peiman Hematti
Journal:  Cytotherapy       Date:  2014-11-21       Impact factor: 5.414

Review 4.  Mesenchymal stem cells: a friend or foe in immune-mediated diseases.

Authors:  Marina Gazdic; Vladislav Volarevic; Nebojsa Arsenijevic; Miodrag Stojkovic
Journal:  Stem Cell Rev Rep       Date:  2015-04       Impact factor: 5.739

5.  Human umbilical cord mesenchymal stromal cells suppress MHC class II expression on rat vascular endothelium and prolong survival time of cardiac allograft.

Authors:  Ying Qiu; Mark M Yun; Xia Han; Ruidong Zhao; Erxia Zhou; Sheng Yun
Journal:  Int J Clin Exp Med       Date:  2014-07-15

Review 6.  Mesenchymal stromal cell therapy for the treatment of intestinal ischemia: Defining the optimal cell isolate for maximum therapeutic benefit.

Authors:  Dominique L Doster; Amanda R Jensen; Sina Khaneki; Troy A Markel
Journal:  Cytotherapy       Date:  2016-10-10       Impact factor: 5.414

Review 7.  Regenerative stromal cell therapy in allogeneic hematopoietic stem cell transplantation: current impact and future directions.

Authors:  Jeffery J Auletta; Kenneth R Cooke; Luis A Solchaga; Robert J Deans; Wouter van't Hof
Journal:  Biol Blood Marrow Transplant       Date:  2009-12-16       Impact factor: 5.742

8.  Mouse bone marrow-derived mesenchymal stromal cells turn activated macrophages into a regulatory-like profile.

Authors:  Julian Maggini; Gerardo Mirkin; Ianina Bognanni; Josefina Holmberg; Isabel M Piazzón; Irene Nepomnaschy; Héctor Costa; Cristian Cañones; Silvina Raiden; Mónica Vermeulen; Jorge R Geffner
Journal:  PLoS One       Date:  2010-02-16       Impact factor: 3.240

Review 9.  Current and future regenerative medicine - principles, concepts, and therapeutic use of stem cell therapy and tissue engineering in equine medicine.

Authors:  Thomas G Koch; Lise C Berg; Dean H Betts
Journal:  Can Vet J       Date:  2009-02       Impact factor: 1.008

10.  Biologic and immunomodulatory properties of mesenchymal stromal cells derived from human pancreatic islets.

Authors:  Jaehyup Kim; Melissa J Breunig; Leah E Escalante; Neehar Bhatia; Ryan A Denu; Bridget A Dollar; Andrew P Stein; Summer E Hanson; Nadia Naderi; James Radek; Dermot Haughy; Debra D Bloom; Fariba M Assadi-Porter; Peiman Hematti
Journal:  Cytotherapy       Date:  2012-05-09       Impact factor: 5.414

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