Literature DB >> 18371417

Why myc? An unexpected ingredient in the stem cell cocktail.

Paul S Knoepfler1.   

Abstract

Screening cocktails of candidate genes for induction of pluripotency and self-renewal in nonstem cells has identified a surprising new embryonic stem cell regulator, the myc proto-oncogene. Here the possible mechanisms by which myc controls self-renewal and pluripotency are discussed.

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Year:  2008        PMID： 18371417     DOI： 10.1016/j.stem.2007.12.004

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  60 in total

1.  Epigenetic reprogramming of Myc target genes.

Authors:  Stefano Amente; Luigi Lania; Barbara Majello
Journal:  Am J Cancer Res       Date:  2011-02-06       Impact factor: 6.166

Review 2.  Induced pluripotency: history, mechanisms, and applications.

Authors:  Matthias Stadtfeld; Konrad Hochedlinger
Journal:  Genes Dev       Date:  2010-10-15       Impact factor: 11.361

Review 3.  Epigenetic reprogramming and induced pluripotency.

Authors:  Konrad Hochedlinger; Kathrin Plath
Journal:  Development       Date:  2009-02       Impact factor: 6.868

Review 4.  Epigenetic memory in development and disease: Unraveling the mechanism.

Authors:  Sam Thiagalingam
Journal:  Biochim Biophys Acta Rev Cancer       Date:  2020-01-23       Impact factor: 10.680

5.  Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis.

Authors:  Bora Gurel; Tsuyoshi Iwata; Cheryl M Koh; Robert B Jenkins; Fusheng Lan; Chi Van Dang; Jessica L Hicks; James Morgan; Toby C Cornish; Siobhan Sutcliffe; William B Isaacs; Jun Luo; Angelo M De Marzo
Journal:  Mod Pathol       Date:  2008-06-20       Impact factor: 7.842

Review 6.  Induced pluripotent stem cells as a model for accelerated patient- and disease-specific drug discovery.

Authors:  I Gunaseeli; M X Doss; C Antzelevitch; J Hescheler; A Sachinidis
Journal:  Curr Med Chem       Date:  2010       Impact factor: 4.530

7.  MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells.

Authors:  Tsuyoshi Iwata; Denise Schultz; Jessica Hicks; Gretchen K Hubbard; Laura N Mutton; Tamara L Lotan; Carlise Bethel; Matthew T Lotz; Srinivasan Yegnasubramanian; William G Nelson; Chi V Dang; MengMeng Xu; Uzoma Anele; Cheryl M Koh; Charles J Bieberich; Angelo M De Marzo
Journal:  PLoS One       Date:  2010-02-25       Impact factor: 3.240

8.  MicroRNA let-7: an emerging next-generation cancer therapeutic.

Authors:  D Barh; R Malhotra; B Ravi; P Sindhurani
Journal:  Curr Oncol       Date:  2010-02       Impact factor: 3.677

9.  N-Myc regulates expression of pluripotency genes in neuroblastoma including lif, klf2, klf4, and lin28b.

Authors:  Rebecca Cotterman; Paul S Knoepfler
Journal:  PLoS One       Date:  2009-06-04       Impact factor: 3.240

Review 10.  Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine.

Authors:  Paul S Knoepfler
Journal:  Stem Cells       Date:  2009-05       Impact factor: 6.277
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