Pasquale Casale1, Kevin Meyers, Bernard Kaplan. 1. Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania 19107, USA. casale@email.chop.edu
Abstract
PURPOSE: To present our medium-term experience with laparoscopic renal denervation and nephropexy for autosomal dominant polycystic kidney disease (ADPKD)-related pain in the pediatric patient. MATERIALS AND METHODS: Twelve patients aged 8 to 19 years (mean age 12.4 years) with ADPKD presented with chronic pain refractory to narcotic analgesics. These 12 patients underwent laparoscopic renal denervation of 16 kidneys. RESULTS: Mean operative time was 152 minutes and mean hospital stay was 2.17 days. All patients were pain-free at discharge and remain pain-free at a mean follow-up of 25.5 months. Three adolescent patients each had an episode of flank pain. One was associated with pyelonephritis, another with stones, and the third with trauma and a hematoma. CONCLUSIONS: Laparoscopic renal denervation and nephropexy is a promising option for pediatric patients with uncontrolled ADPKD-related pain.
PURPOSE: To present our medium-term experience with laparoscopic renal denervation and nephropexy for autosomal dominant polycystic kidney disease (ADPKD)-related pain in the pediatric patient. MATERIALS AND METHODS: Twelve patients aged 8 to 19 years (mean age 12.4 years) with ADPKD presented with chronic pain refractory to narcotic analgesics. These 12 patients underwent laparoscopic renal denervation of 16 kidneys. RESULTS: Mean operative time was 152 minutes and mean hospital stay was 2.17 days. All patients were pain-free at discharge and remain pain-free at a mean follow-up of 25.5 months. Three adolescent patients each had an episode of flank pain. One was associated with pyelonephritis, another with stones, and the third with trauma and a hematoma. CONCLUSIONS: Laparoscopic renal denervation and nephropexy is a promising option for pediatric patients with uncontrolled ADPKD-related pain.
Authors: Ragada El-Damanawi; Michael Lee; Tess Harris; Laura B Cowley; Ingrid Scholtes; Simon Bond; Richard N Sandford; Ian B Wilkinson; Niek F Casteleijn; Marie C Hogan; Fiona E Karet Frankl; Thomas F Hiemstra Journal: Clin Kidney J Date: 2021-02-08