Literature DB >> 18369971

Extended-release oral drug delivery technologies: monolithic matrix systems.

Sandip B Tiwari1, Ali R Rajabi-Siahboomi.   

Abstract

Oral drug delivery is the largest and the oldest segment of the total drug delivery market. It is the fastest growing and most preferred route for drug administration. Use of hydrophilic matrices for oral extended release of drugs is a common practice in the pharmaceutical industry. This chapter presents different polymer choices for fabrication of monolithic hydrophilic matrices and discusses formulation and manufacturing variables affecting the design and performance of the extended-release product by using selected practical examples.

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Year:  2008        PMID: 18369971     DOI: 10.1007/978-1-59745-210-6_11

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  9 in total

1.  Development of sustained release capsules containing "coated matrix granules of metoprolol tartrate".

Authors:  Sabahuddin Siddique; Jasmina Khanam; Papiya Bigoniya
Journal:  AAPS PharmSciTech       Date:  2010-08-19       Impact factor: 3.246

2.  Controlled release of ropinirole hydrochloride from a multiple barrier layer tablet dosage form: effect of polymer type on pharmacokinetics and IVIVC.

Authors:  Nikhil Malewar; Makarand Avachat; Varsha Pokharkar; Shirish Kulkarni
Journal:  AAPS PharmSciTech       Date:  2013-07-30       Impact factor: 3.246

3.  Development and characterization of solid dispersion-microsphere controlled release system for poorly water-soluble drug.

Authors:  Venkata Ramana Malipeddi; Kamal Dua; Rajendra Awasthi
Journal:  Drug Deliv Transl Res       Date:  2016-10       Impact factor: 4.617

4.  Combined use of crystalline sodium salt and polymeric precipitation inhibitors to improve pharmacokinetic profile of ibuprofen through supersaturation.

Authors:  Jenna L Terebetski; John J Cummings; Scott E Fauty; Bozena Michniak-Kohn
Journal:  AAPS PharmSciTech       Date:  2014-06-12       Impact factor: 3.246

5.  Zero-order release of poorly water-soluble drug from polymeric films made via aqueous slurry casting.

Authors:  Lu Zhang; Joy Alfano; Doran Race; Rajesh N Davé
Journal:  Eur J Pharm Sci       Date:  2018-02-27       Impact factor: 4.384

6.  The influence of sodium carboxymethylcellulose on drug release from polyethylene oxide extended release matrices.

Authors:  Dasha Palmer; Marina Levina; Ali Nokhodchi; Dennis Douroumis; Tom Farrell; Ali Rajabi-Siahboomi
Journal:  AAPS PharmSciTech       Date:  2011-06-28       Impact factor: 3.246

Review 7.  Micro/nanofabricated platforms for oral drug delivery.

Authors:  Cade B Fox; Jean Kim; Long V Le; Cameron L Nemeth; Hariharasudhan D Chirra; Tejal A Desai
Journal:  J Control Release       Date:  2015-08-02       Impact factor: 9.776

8.  Application of ethylcellulose coating to hydrophilic matrices: a strategy to modulate drug release profile and reduce drug release variability.

Authors:  Raxit Y Mehta; Shahrzad Missaghi; Sandip B Tiwari; Ali R Rajabi-Siahboomi
Journal:  AAPS PharmSciTech       Date:  2014-05-22       Impact factor: 3.246

9.  Oral delivery of metformin by chitosan nanoparticles for polycystic kidney disease.

Authors:  Jonathan Wang; Deborah Chin; Christopher Poon; Valeria Mancino; Jessica Pham; Hui Li; Pei-Yin Ho; Kenneth R Hallows; Eun Ji Chung
Journal:  J Control Release       Date:  2020-10-28       Impact factor: 9.776

  9 in total

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