N Malila1, T Oivanen, M Hakama. 1. Finnish Cancer Registry, Mass Screening Registry, Helsinki, Finland. nea.malila@cancer.fi
Abstract
BACKGROUND AND STUDY AIMS: Colorectal cancer mortality can be reduced by repeated screening, using faecal occult blood testing. This report describes the implementation of service screening in Finland and performance indicators from the first three years. METHODS: The programme is based on gradual expansion over six years of implementation. It involves individual-level randomisation into screening or control arms among a target population of men and women aged 60-69 years. The effects will be evaluated comparing incidence of and mortality from colorectal cancer in the invited arm with the controls. The screening test is a biannual guaiac-based faecal occult blood test with three test cards for consecutive samples and colonoscopies offered to those with any blood observed. RESULTS:Between September 2004 and December 2006, 52,994 test kits (to 26,247 men and 26,747 women) were sent out in 160 municipalities out of 444. Attendance to screening was 71% overall, 63% in men and 78% in women. People from the youngest age-group (born in 1946) were less compliant than those from the oldest one (born in 1940). Among the screened, 2.1% were found with blood in the stools, 3% of men and 1.5% of women. Cancers and adenomas were detected according to expectations, in 8.6 and 43.2%, respectively, among those who underwent colonoscopy. CONCLUSIONS: The implementation measured with attendance and performance of the test of colorectal cancer screening in Finland has been successful. The programme meets the criteria both for a randomised trial and for a public health programme allowing unbiased data to be collected during the implementation period.
RCT Entities:
BACKGROUND AND STUDY AIMS: Colorectal cancer mortality can be reduced by repeated screening, using faecal occult blood testing. This report describes the implementation of service screening in Finland and performance indicators from the first three years. METHODS: The programme is based on gradual expansion over six years of implementation. It involves individual-level randomisation into screening or control arms among a target population of men and women aged 60-69 years. The effects will be evaluated comparing incidence of and mortality from colorectal cancer in the invited arm with the controls. The screening test is a biannual guaiac-based faecal occult blood test with three test cards for consecutive samples and colonoscopies offered to those with any blood observed. RESULTS: Between September 2004 and December 2006, 52,994 test kits (to 26,247 men and 26,747 women) were sent out in 160 municipalities out of 444. Attendance to screening was 71% overall, 63% in men and 78% in women. People from the youngest age-group (born in 1946) were less compliant than those from the oldest one (born in 1940). Among the screened, 2.1% were found with blood in the stools, 3% of men and 1.5% of women. Cancers and adenomas were detected according to expectations, in 8.6 and 43.2%, respectively, among those who underwent colonoscopy. CONCLUSIONS: The implementation measured with attendance and performance of the test of colorectal cancer screening in Finland has been successful. The programme meets the criteria both for a randomised trial and for a public health programme allowing unbiased data to be collected during the implementation period.
Authors: Ulrik Deding; Anna Sharon Henig; Ann Salling; Christian Torp-Pedersen; Henrik Bøggild Journal: Int J Colorectal Dis Date: 2017-05-13 Impact factor: 2.571
Authors: D Major; H Bryant; M Delaney; S Fekete; L Gentile; M Harrison; V Mai; E Nicholson; Y Taylor Journal: Curr Oncol Date: 2013-10 Impact factor: 3.677
Authors: J Pitkäniemi; K Seppä; M Hakama; O Malminiemi; T Palva; M-S Vuoristo; H Järvinen; H Paimela; P Pikkarainen; A Anttila; L Elovainio; T Hakulinen; S Karjalainen; L Pylkkänen; M Rautalahti; T Sarkeala; H Vertio; N Malila Journal: BMJ Open Gastroenterol Date: 2015-06-08
Authors: Linda Sharp; Lesley Tilson; Sophie Whyte; Alan O Ceilleachair; Cathal Walsh; Cara Usher; Paul Tappenden; James Chilcott; Anthony Staines; Michael Barry; Harry Comber Journal: BMC Health Serv Res Date: 2013-03-19 Impact factor: 2.655
Authors: Catharina G M Groothuis-Oudshoorn; Jilles M Fermont; Janine A van Til; Maarten J Ijzerman Journal: BMC Med Inform Decis Mak Date: 2014-03-19 Impact factor: 2.796