| Literature DB >> 18368554 |
Mandy Weselak1, Tye E Arbuckle, Mark C Walker, Daniel Krewski.
Abstract
It is estimated that close to 30% of all pregnancies end in spontaneous abortion. Although about 60% of spontaneous abortions are thought to be due to genetic, infectious, hormonal, and immunological factors, the role of the environment remains poorly understood. Pregnancy involves a delicate balance of hormonal and immunological functions, which may be affected by environmental substances. Many toxic substances that are persistent in the environment and accumulate in the fatty tissues may disrupt this equilibrium. This overview addresses known risk factors for spontaneous abortions and examines the role, if any, that environmental factors (chemical and physical) may play in the etiology of this adverse health outcome.Entities:
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Year: 2008 PMID： 18368554 DOI： 10.1080/10937400701873530
Source DB: PubMed Journal: J Toxicol Environ Health B Crit Rev ISSN： 1093-7404 Impact factor: 6.393