Literature DB >> 18367362

Estimation and characterisation of budesonide tablets impurities.

Patrizia Ferraboschi1, Vittorio Bertacche, Isabella Maccone, Elena Pini, Laura Ragonesi, Alessio Venturini, Riccardo Stradi.   

Abstract

Budesonide is the 16alpha,17alpha-acetal of 16alpha-hydroxyprednisolone with n-butyraldehyde, endowed with anti-inflammatory activity. In a sample of budesonide tablets, kept for 3 years at 25 degrees C and 60% RH unknown impurities, not reported in European Pharmacopoiea, were present. Their identification was achieved by means of chemical and spectroscopic methods.

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Year:  2008        PMID: 18367362     DOI: 10.1016/j.jpba.2008.01.050

Source DB:  PubMed          Journal:  J Pharm Biomed Anal        ISSN: 0731-7085            Impact factor:   3.935


  1 in total

1.  Development and validation of a rapid HPLC method for simultaneous analysis of budesonide and its novel synthesized hemiesters in colon specific formulations.

Authors:  J Varshosaz; J Emami; N Tavakoli; M Minaiyan; N Rahmani; F Ahmadi; F Dorkoosh
Journal:  Res Pharm Sci       Date:  2011-07
  1 in total

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