| Literature DB >> 1836486 |
A D Harries1, M Clark, N J Beeching, J Lavelle, K J Mutton.
Abstract
A significantly higher prevalence of a protective concentration of anti-HBs was achieved at 1 and 2 months among 132 healthy medical students who received an accelerated vaccination schedule with a recombinant hepatitis B vaccine (Engerix-B) than among 120 medical students who received a conventional regimen. With the accelerated schedule, however, 60% students at 1 month and 27% at 2 months were still unprotected (anti-HBs titre less than 10.0 IU/l). Additional passive immunisation should therefore continue to be offered if the accelerated schedule is adopted for post-exposure prophylaxis.Entities:
Keywords: Antibodies; Antigen-antibody Reactions; Asians; Behavior; Biology; Body Height; Body Weight; Comparative Studies; Contraception; Contraceptive Methods; Cultural Background; Delivery Of Health Care; Demographic Factors; Developed Countries; Diseases; Education; England; Ethnic Groups; Europe; Family Planning; Health; Health Services; Hepatic Effects; Immunity; Immunization; Immunologic Factors; Medical Students; Methodological Studies; Northern Europe; Oral Contraceptives; Physiology; Population; Population Characteristics; Primary Health Care; Research Methodology; Smoking; Students; Studies; United Kingdom; Vaccination; Viral Diseases
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Year: 1991 PMID： 1836486 DOI： 10.1016/0163-4453(91)92792-4
Source DB: PubMed Journal: J Infect ISSN： 0163-4453 Impact factor: 6.072