BACKGROUND: Childhood is a critical period for naevogenesis. OBJECTIVE: To describe the prevalence of dermoscopic patterns of naevi using cross-sectional data from a population-based cohort of children. METHODS: We obtained overview digital photography of the back of fifth graders (age 10-11 years) from all 10 schools in Framingham, MA, U.S.A. From each participant, dermoscopic images of up to four naevi were obtained, including the largest and one randomly selected naevus on the upper back and a corresponding pair from the lower back. RESULTS: The study included 443 children, 61% boys, with 1181 back naevi analysed. Globular pattern was seen in 37% of naevi, reticular pattern in 13%, homogeneous pattern in 44% and complex (reticular-globular) dermoscopic pattern in 5%. Globular naevi were significantly more frequent and larger on the upper than the lower back. There was a significant hierarchic trend in naevus diameter by dermoscopic pattern: complex naevi (4.3 mm)>globular (3.3 mm)>reticular (3.0 mm)>homogeneous (2.8 mm). Reticular naevi were more prevalent in children with darker pigment phenotype (P<0.0001). There was a decrease in the size of naevi in children with darker pigmentation (P<0.0001). CONCLUSIONS: An interrelationship was observed in childhood between dermoscopic pattern, naevus size, anatomical location on the back and pigment phenotype.
BACKGROUND: Childhood is a critical period for naevogenesis. OBJECTIVE: To describe the prevalence of dermoscopic patterns of naevi using cross-sectional data from a population-based cohort of children. METHODS: We obtained overview digital photography of the back of fifth graders (age 10-11 years) from all 10 schools in Framingham, MA, U.S.A. From each participant, dermoscopic images of up to four naevi were obtained, including the largest and one randomly selected naevus on the upper back and a corresponding pair from the lower back. RESULTS: The study included 443 children, 61% boys, with 1181 back naevi analysed. Globular pattern was seen in 37% of naevi, reticular pattern in 13%, homogeneous pattern in 44% and complex (reticular-globular) dermoscopic pattern in 5%. Globular naevi were significantly more frequent and larger on the upper than the lower back. There was a significant hierarchic trend in naevus diameter by dermoscopic pattern: complex naevi (4.3 mm)>globular (3.3 mm)>reticular (3.0 mm)>homogeneous (2.8 mm). Reticular naevi were more prevalent in children with darker pigment phenotype (P<0.0001). There was a decrease in the size of naevi in children with darker pigmentation (P<0.0001). CONCLUSIONS: An interrelationship was observed in childhood between dermoscopic pattern, naevus size, anatomical location on the back and pigment phenotype.
Authors: Haoming Xu; Xinyuan Wu; Esther Chung; Maira Fonseca; Stephen W Dusza; Alon Scope; Alan C Geller; Marilyn Bishop; Ashfaq A Marghoob; Allan C Halpern; Michael A Marchetti Journal: J Invest Dermatol Date: 2019-02-22 Impact factor: 8.551
Authors: Christiane Donato Piazza; Sergio Yamada; Aline P Marcassi; Marina G Maciel; Maria P Seize; Silmara C P Cestari Journal: An Bras Dermatol Date: 2017 May-Jun Impact factor: 1.896
Authors: M Fonseca; M A Marchetti; E Chung; S W Dusza; M E Burnett; A A Marghoob; A C Geller; M Bishop; A Scope; A C Halpern Journal: Br J Dermatol Date: 2015-10-27 Impact factor: 9.302
Authors: Alon Scope; Michael A Marchetti; Ashfaq A Marghoob; Stephen W Dusza; Alan C Geller; Jaya M Satagopan; Martin A Weinstock; Marianne Berwick; Allan C Halpern Journal: J Am Acad Dermatol Date: 2016-06-17 Impact factor: 11.527
Authors: Haoming Xu; Michael A Marchetti; Stephen W Dusza; Esther Chung; Maira Fonseca; Alon Scope; Alan C Geller; Marilyn Bishop; Ashfaq A Marghoob; Allan C Halpern Journal: JAMA Dermatol Date: 2017-10-01 Impact factor: 10.282
Authors: Tova Rogers; Maria L Marino; Patricia Raciti; Manu Jain; Klaus J Busam; Michael A Marchetti; Ashfaq A Marghoob Journal: G Ital Dermatol Venereol Date: 2016-04-27 Impact factor: 2.011
Authors: Alon Scope; Stephen W Dusza; Ashfaq A Marghoob; Jaya M Satagopan; Juliana Braga Casagrande Tavoloni; Estee L Psaty; Martin A Weinstock; Susan A Oliveria; Marilyn Bishop; Alan C Geller; Allan C Halpern Journal: J Invest Dermatol Date: 2011-05-12 Impact factor: 8.551