Literature DB >> 18362463

Thoracic spinal epidural abscess caused by Salmonella typhi.

Saad Hamdan Abdullah1, Osama Abu Ata, Nael El-Adwan.   

Abstract

A 56-year-old man presented with a rare spinal epidural abscess manifesting as attacks of back pain associated with fever, weight loss, generalized weakness and fatigability, and constipation. He had multiple skin pustules in the last 4 months treated with oral amoxicillin. He had suffered diabetes mellitus for the last 5 years and was insulin dependent. Physical examination found slight paraparesis with sensory loss around the nipple and sphincteric urgency, and diabetic retinopathy. Magnetic resonance imaging showed edematous T2, T3, and T4 vertebral bodies, and narrow enhanced T3-4 disk space with a soft tissue enhanced mass mostly anterior to the spinal cord and indenting the cord. T3-4 costotransversectomy was performed to remove the extradural mass and evacuate the intradiscal material. Histological examination of the bone found osteomyelitis, and culture of the soft tissue showed Salmonella typhi sensitive to ceftriaxone and ciprofloxacin. Intravenous ceftriaxone administration was started, and the patient was discharged after 6 days in good condition. The outcome of spinal epidural abscess is devastating unless recognized and treated early. The present case of spinal epidural abscess in the thoracic spine caused by Salmonella typhi infection illustrates the importance of cultures to assess the drug sensitivity of the specific strain detected and adjusting the treatment accordingly.

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Year:  2008        PMID: 18362463     DOI: 10.2176/nmc.48.140

Source DB:  PubMed          Journal:  Neurol Med Chir (Tokyo)        ISSN: 0470-8105            Impact factor:   1.742


  4 in total

Review 1.  Anterior spinal epidural abscess due to Salmonella typhi: a report of a rare case treated conservatively and review of the literature.

Authors:  Antonio Nardone; Federico Caporlingua; Gennaro Lapadula; Antonio Santoro
Journal:  Neurol Sci       Date:  2013-03-30       Impact factor: 3.307

2.  Bug on the back: vertebral osteomyelitis secondary to fluoroquinolone resistant Salmonella typhi in an immunocompetent patient.

Authors:  Pragya Shrestha; Sachin Mohan; Satyajeet Roy
Journal:  BMJ Case Rep       Date:  2015-11-27

3.  Spinal Abscess Caused by Salmonella Bacteremia in a Patient with Primary Myelofibrosis.

Authors:  Shehab Fareed; Abdulqadir J Nashwan; Sulieman Abu Jarir; Ahmed Husain; Dina Sameh Suliman; Friyal Ibrahim; Abbas Moustafa; Muhammad S Akhter; Mohamed A Yassin
Journal:  Am J Case Rep       Date:  2017-08-04

4.  Salmonella Typhi Vertebral Osteomyelitis and Epidural Abscess.

Authors:  Hau Wei Khoo; Ying Ying Chua; John L T Chen
Journal:  Case Rep Orthop       Date:  2016-03-10
  4 in total

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