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Literature DB >> 18362220

VKORC1 Asp36Tyr warfarin resistance marker is common in Ethiopian individuals.

Eleni Aklillu, Cheryl Leong, Ronen Loebstein, Hillel Halkin, Eva Gak.

Abstract

Entities: Gene Mutation

Mesh：

Substances：

Year: 2008 PMID： 18362220 DOI： 10.1182/blood-2008-01-135863

Source DB: PubMed Journal: Blood ISSN： 0006-4971 Impact factor: 22.113

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18 in total

1. CYP4F2 rs2108622: a minor significant genetic factor of warfarin dose in Han Chinese patients with mechanical heart valve replacement.

Authors: Han-Jing Cen; Wu-Tao Zeng; Xiu-Yu Leng; Min Huang; Xiao Chen; Jia-Li Li; Zhi-Ying Huang; Hui-Chang Bi; Xue-Ding Wang; Yan-Ling He; Fan He; Rui-Na Zhou; Qi-Shan Zheng; Li-Zi Zhao
Journal: Br J Clin Pharmacol Date: 2010-08 Impact factor: 4.335

2. Absence of novel CYP4F2 and VKORC1 coding region DNA variants in patients requiring high warfarin doses.

Authors: James K Burmester; Richard L Berg; Ingrid Glurich; Steven H Yale; John R Schmelzer; Michael D Caldwell
Journal: Clin Med Res Date: 2011-05-11

Review 3. Recommendations for Clinical Warfarin Genotyping Allele Selection: A Report of the Association for Molecular Pathology and the College of American Pathologists.

Authors: Victoria M Pratt; Larisa H Cavallari; Andria L Del Tredici; Houda Hachad; Yuan Ji; Lisa V Kalman; Reynold C Ly; Ann M Moyer; Stuart A Scott; Michelle Whirl-Carrillo; Karen E Weck
Journal: J Mol Diagn Date: 2020-05-04 Impact factor: 5.568

4. Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups.

Authors: Nita A Limdi; Mia Wadelius; Larisa Cavallari; Niclas Eriksson; Dana C Crawford; Ming-Ta M Lee; Chien-Hsiun Chen; Alison Motsinger-Reif; Hersh Sagreiya; Nianjun Liu; Alan H B Wu; Brian F Gage; Andrea Jorgensen; Munir Pirmohamed; Jae-Gook Shin; Guilherme Suarez-Kurtz; Stephen E Kimmel; Julie A Johnson; Teri E Klein; Michael J Wagner
Journal: Blood Date: 2010-03-04 Impact factor: 22.113

VKORC1 Asp36Tyr warfarin resistance marker is common in Ethiopian individuals.

1. CYP4F2 rs2108622: a minor significant genetic factor of warfarin dose in Han Chinese patients with mechanical heart valve replacement.

2. Absence of novel CYP4F2 and VKORC1 coding region DNA variants in patients requiring high warfarin doses.

Review 3. Recommendations for Clinical Warfarin Genotyping Allele Selection: A Report of the Association for Molecular Pathology and the College of American Pathologists.

4. Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups.

5. Effect of the VKORC1 D36Y variant on warfarin dose requirement and pharmacogenetic dose prediction.

6. CYP2C9*8 is prevalent among African-Americans: implications for pharmacogenetic dosing.

7. Personalized healthcare in clotting disorders.

8. Inhibition of bacterial disulfide bond formation by the anticoagulant warfarin.

Review 9. Effect of genetic variants, especially CYP2C9 and VKORC1, on the pharmacology of warfarin.

10. The VKORC1 Asp36Tyr variant and VKORC1 haplotype diversity in Ashkenazi and Ethiopian populations.