| Literature DB >> 18361945 |
Helen Giamarellou1, Kyriaki Kanellakopoulou.
Abstract
Based on the worldwide prevalence of multidrug-resistant strains of Pseudomas aeruginosa and the fact that no newer antipseudomonal agents are available, this article aims to investigate therapeutic solutions for combating infections caused by P aeruginosa, including multidrug-resistant strains. The article focuses mainly on colistin, the re-emerging old antibiotic that possesses prominent antipseudomonal activity in vitro and on doripenem, a newer carbapenem that seems to be close to its global marketing. Regarding older antipseudomonal antibiotics that have been reviewed extensively, only newer aspects on their use are considered in this article.Entities:
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Year: 2008 PMID: 18361945 DOI: 10.1016/j.ccc.2007.12.004
Source DB: PubMed Journal: Crit Care Clin ISSN: 0749-0704 Impact factor: 3.598