Literature DB >> 18361259

In chronic disease, nationwide data show poor adherence by patients to medication and by physicians to guidelines.

Sara L Thier1, Kristina S Yu-Isenberg, Brian F Leas, C Ron Cantrell, Sandra DeBussey, Neil I Goldfarb, David B Nash.   

Abstract

PURPOSE: It is widely acknowledged in small studies that provider variation from evidence-based care guidelines and patient medication nonadherence lead to less than optimal health outcomes, increasing costs, and higher utilization. The research presented here aims to determine the prevalence of patient adherence to a medication regimen and provider adherence to guidelines for a variety of chronic conditions, using nationally representative data.
DESIGN: A retrospective analysis of administrative claims data from a large national insurer was conducted.
METHODOLOGY: The study examined multiple quality indicators exemplifying evidence-based medicine and medication adherence for several chronic conditions. Medication possession ratio (MPR) determined patient adherence. Using EBM Connect software created by Ingenix, we measured adherence to guidelines by applying a series of clinical rules and algorithms. PRINCIPAL
FINDINGS: Adherence to the evidence-based practice guidelines examined in this study averaged approximately 59 percent, while patient medication nonadherence rates for all the conditions studied averaged 26.2 percent, with a range of 11 percent to 42 percent. Physician adherence to guidelines was highest in the prescribing of inhaled corticosteroids for persistent asthma. Ironically, medication adherence rates for inhaled corticosteroids were the worst identified. The best medication adherence rate was observed in patients with hypertension.
CONCLUSION: Like earlier studies, this analysis finds that poor adherence is common across the nation and across common chronic conditions.

Entities:  

Mesh:

Year:  2008        PMID: 18361259

Source DB:  PubMed          Journal:  Manag Care        ISSN: 1062-3388


  24 in total

1.  Development of a computer system to support medication reviews in nursing homes.

Authors:  Hugo A J M de Wit; Carlota Mestres Gonzalvo; Kim P G M Hurkens; Wubbo J Mulder; Rob Janknegt; Frans R Verhey; Jos M G A Schols; Paul-Hugo M van der Kuy
Journal:  Int J Clin Pharm       Date:  2013-10

2.  Development of a Multilevel Framework to Increase Use of Targeted Evidence-Based Practices in Addiction Treatment Clinics.

Authors:  Todd Molfenter; Dennis McCarty; Victor Capoccia; David Gustafson
Journal:  Public Health Front       Date:  2013-03-01

3.  The h-e-B value-based health management program: impact on asthma medication adherence and healthcare cost.

Authors:  Anna O D'Souza; Roshan Rahnama; Timothy S Regan; Beth Common; Steven Burch
Journal:  Am Health Drug Benefits       Date:  2010-11

4.  Lower copay and oral administration: predictors of first-fill adherence to new asthma prescriptions.

Authors:  Zackary Berger; William Kimbrough; Colleen Gillespie; Joseph A Boscarino; G Craig Wood; Zhengmin Qian; J B Jones; Nirav R Shah
Journal:  Am Health Drug Benefits       Date:  2009-06

5.  Use of health information technology to improve medication adherence.

Authors:  William M Vollmer; Adrianne Feldstein; David H Smith; Joan P Dubanoski; Amy Waterbury; Jennifer L Schneider; Shelley A Clark; Cynthia Rand
Journal:  Am J Manag Care       Date:  2011-12       Impact factor: 2.229

6.  Predictors of medication adherence: fact or artifact.

Authors:  Jacqueline Dunbar-Jacob; Jeffrey M Rohay
Journal:  J Behav Med       Date:  2016-06-15

7.  Social Risk Factors for Medication Nonadherence: Findings from the CARDIA Study.

Authors:  Gabriela R Oates; Lucia D Juarez; Barbara Hansen; Catarina I Kiefe; James M Shikany
Journal:  Am J Health Behav       Date:  2020-03-01

8.  Predictors of first-fill adherence for patients with hypertension.

Authors:  Nirav R Shah; Annemarie G Hirsch; Christopher Zacker; G Craig Wood; Antoinette Schoenthaler; Gbenga Ogedegbe; Walter F Stewart
Journal:  Am J Hypertens       Date:  2009-01-29       Impact factor: 2.689

9.  A multifaceted intervention to improve blood pressure control: The Guideline Adherence for Heart Health (GLAD) study.

Authors:  Denise E Bonds; Patricia E Hogan; Alain G Bertoni; Haiying Chen; C Randall Clinch; Ann E Hiott; Erica L Rosenberger; David C Goff
Journal:  Am Heart J       Date:  2008-11-20       Impact factor: 4.749

10.  Components of recommended asthma care and the use of long-term control medication among urban children with asthma.

Authors:  Jeanette Anne Stingone; Luz Claudio
Journal:  Med Care       Date:  2009-09       Impact factor: 2.983

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