Literature DB >> 18359053

Unscrupulous marketing of snake bite antivenoms in Africa and Papua New Guinea: choosing the right product--'what's in a name?'.

David A Warrell1.   

Abstract

Snake bite envenoming, mainly caused by the saw-scaled or carpet viper (Echis ocellatus), is a neglected disease of West Africa. Specific antivenoms can save life and limb but, for various reasons, supply of these essential drugs to Africa has dwindled to less than 2% of estimated requirements. Other problems include maldistribution, inadequate conservation and inappropriate clinical use of antivenoms. In the face of this crisis, several promising new antivenoms have been developed. However, some dangerously inappropriate products of Indian origin are being marketed by unscrupulous manufacturers or distributors in Africa and Papua New Guinea, with disastrous results. A major source of confusion is labelling antivenom with ambiguous snake names that fail to distinguish the Asian species whose venoms are used in their production from the local snakes whose venoms are antigenically dissimilar.

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Year:  2008        PMID: 18359053     DOI: 10.1016/j.trstmh.2007.12.005

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


  21 in total

1.  Antivenomic assessment of the immunological reactivity of EchiTAb-Plus-ICP, an antivenom for the treatment of snakebite envenoming in sub-Saharan Africa.

Authors:  Juan J Calvete; Pedro Cid; Libia Sanz; Alvaro Segura; Mauren Villalta; María Herrera; Guillermo León; Robert Harrison; Nandul Durfa; Abdusalami Nasidi; R David G Theakston; David A Warrell; José María Gutiérrez
Journal:  Am J Trop Med Hyg       Date:  2010-06       Impact factor: 2.345

2.  Management of snake bites in the tropics - based on the example of Papua New Guinea.

Authors:  Martin Haditsch
Journal:  Wien Klin Wochenschr       Date:  2009-10       Impact factor: 1.704

3.  Snake envenoming: a disease of poverty.

Authors:  Robert A Harrison; Adam Hargreaves; Simon C Wagstaff; Brian Faragher; David G Lalloo
Journal:  PLoS Negl Trop Dis       Date:  2009-12-22

4.  Randomised controlled double-blind non-inferiority trial of two antivenoms for saw-scaled or carpet viper (Echis ocellatus) envenoming in Nigeria.

Authors:  Isa S Abubakar; Saidu B Abubakar; Abdulrazaq G Habib; Abdulsalam Nasidi; Nandul Durfa; Peter O Yusuf; Solomon Larnyang; John Garnvwa; Elijah Sokomba; Lateef Salako; R David G Theakston; Ed Juszczak; Nicola Alder; David A Warrell
Journal:  PLoS Negl Trop Dis       Date:  2010-07-27

5.  Envenoming after carpet viper (Echis ocellatus) bite during pregnancy: timely use of effective antivenom improves maternal and foetal outcomes.

Authors:  A G Habib; S B Abubakar; I S Abubakar; S Larnyang; N Durfa; A Nasidi; P O Yusuf; J Garnvwa; R D G Theakston; L Salako; D A Warrell
Journal:  Trop Med Int Health       Date:  2008-07-08       Impact factor: 2.622

6.  A multicomponent strategy to improve the availability of antivenom for treating snakebite envenoming.

Authors:  José María Gutiérrez; Thierry Burnouf; Robert A Harrison; Juan J Calvete; Ulrich Kuch; David A Warrell; David J Williams
Journal:  Bull World Health Organ       Date:  2014-03-04       Impact factor: 9.408

7.  Consequences of neglect: analysis of the sub-Saharan African snake antivenom market and the global context.

Authors:  Nicholas I Brown
Journal:  PLoS Negl Trop Dis       Date:  2012-06-05

8.  Comparative venom gland transcriptome surveys of the saw-scaled vipers (Viperidae: Echis) reveal substantial intra-family gene diversity and novel venom transcripts.

Authors:  Nicholas R Casewell; Robert A Harrison; Wolfgang Wüster; Simon C Wagstaff
Journal:  BMC Genomics       Date:  2009-11-30       Impact factor: 3.969

9.  Citizen science and online data: Opportunities and challenges for snake ecology and action against snakebite.

Authors:  Andrew M Durso; Rafael Ruiz de Castañeda; Camille Montalcini; M Rosa Mondardini; Jose L Fernandez-Marques; François Grey; Martin M Müller; Peter Uetz; Benjamin M Marshall; Russell J Gray; Christopher E Smith; Donald Becker; Michael Pingleton; Jose Louies; Arthur D Abegg; Jeannot Akuboy; Gabriel Alcoba; Jennifer C Daltry; Omar M Entiauspe-Neto; Paul Freed; Marco Antonio de Freitas; Xavier Glaudas; Song Huang; Tianqi Huang; Yatin Kalki; Yosuke Kojima; Anne Laudisoit; Kul Prasad Limbu; José G Martínez-Fonseca; Konrad Mebert; Mark-Oliver Rödel; Sara Ruane; Manuel Ruedi; Andreas Schmitz; Sarah A Tatum; Frank Tillack; Avinash Visvanathan; Wolfgang Wüster; Isabelle Bolon
Journal:  Toxicon X       Date:  2021-06-22

10.  Dealing with snakebite in rural Cameroon: A qualitative investigation among victims and traditional healers.

Authors:  Manon Chuat; Gabriel Alcoba; Justin Eyong; Franck Wanda; Eric Comte; Armand Nkwescheu; François Chappuis; Patricia Hudelson
Journal:  Toxicon X       Date:  2021-07-15
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