Literature DB >> 18358801

SKNy worms and long life.

Heinrich Jasper1.   

Abstract

Interactions between insulin signaling and stress-response pathways can markedly impact life span. In this issue, Tullet et al. (2008) demonstrate that the worm homolog of Nrf2, called SKN-1, a transcription factor that switches on expression of antioxidant genes, is an important component of such signaling interactions.

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Year:  2008        PMID: 18358801     DOI: 10.1016/j.cell.2008.03.002

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  13 in total

Review 1.  Are reactive oxygen species always detrimental to pathogens?

Authors:  Claudia N Paiva; Marcelo T Bozza
Journal:  Antioxid Redox Signal       Date:  2013-10-26       Impact factor: 8.401

2.  Nrf2, a guardian of healthspan and gatekeeper of species longevity.

Authors:  Kaitlyn N Lewis; James Mele; John D Hayes; Rochelle Buffenstein
Journal:  Integr Comp Biol       Date:  2010-05-06       Impact factor: 3.326

Review 3.  Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent.

Authors:  Karl A Rodriguez; Ewa Wywial; Viviana I Perez; Adriant J Lambert; Yael H Edrey; Kaitlyn N Lewis; Kelly Grimes; Merry L Lindsey; Martin D Brand; Rochelle Buffenstein
Journal:  Curr Pharm Des       Date:  2011       Impact factor: 3.116

4.  Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response.

Authors:  Zoltan Ungvari; Lora Bailey-Downs; Danuta Sosnowska; Tripti Gautam; Peter Koncz; Gyorgy Losonczy; Praveen Ballabh; Rafael de Cabo; William E Sonntag; Anna Csiszar
Journal:  Am J Physiol Heart Circ Physiol       Date:  2011-05-20       Impact factor: 4.733

5.  Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation.

Authors:  Gabor A Fulop; Tamas Kiss; Stefano Tarantini; Priya Balasubramanian; Andriy Yabluchanskiy; Eszter Farkas; Ferenc Bari; Zoltan Ungvari; Anna Csiszar
Journal:  Geroscience       Date:  2018-11-23       Impact factor: 7.713

6.  Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta.

Authors:  Zoltan Ungvari; Lora Bailey-Downs; Tripti Gautam; Danuta Sosnowska; Mingyi Wang; Robert E Monticone; Richard Telljohann; John T Pinto; Raphael de Cabo; William E Sonntag; Edward G Lakatta; Anna Csiszar
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2011-05-28       Impact factor: 6.053

7.  The WD40 repeat protein WDR-23 functions with the CUL4/DDB1 ubiquitin ligase to regulate nuclear abundance and activity of SKN-1 in Caenorhabditis elegans.

Authors:  Keith P Choe; Aaron J Przybysz; Kevin Strange
Journal:  Mol Cell Biol       Date:  2009-03-09       Impact factor: 4.272

8.  Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf.

Authors:  Riva P Oliveira; Jess Porter Abate; Kieran Dilks; Jessica Landis; Jasmine Ashraf; Coleen T Murphy; T Keith Blackwell
Journal:  Aging Cell       Date:  2009-07-03       Impact factor: 9.304

9.  Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats.

Authors:  Agnes Csiszár; Anna Csiszar; John T Pinto; Tripti Gautam; Christian Kleusch; Bernd Hoffmann; Zsuzsanna Tucsek; Peter Toth; William E Sonntag; Zoltan Ungvari
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2014-03-18       Impact factor: 6.053

10.  Stress resistance in the naked mole-rat: the bare essentials - a mini-review.

Authors:  Kaitlyn N Lewis; James Mele; Peter J Hornsby; Rochelle Buffenstein
Journal:  Gerontology       Date:  2012-05-10       Impact factor: 5.140

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