BACKGROUND: The metabolic syndrome (MS) is associated to a significant increase in the risk of diabetes, coronary heart disease and stroke, resulting in a 5-fold increase of the cardiovascular death rate. AIM: To determine the relationship between gestational diabetes (GD) and the development of MS at the end of puerperal period. PATIENTS AND METHODS: We conducted a case-control study in the Curanilahue Hospital, in southern Chile, including 58 women with GD during their pregnancy, studied in day 42 of their puerperal period (study group) and 58 puerperal women from the same hospital, who had a physiological pregnancy (control group). Triglycerides, HDL cholesterol, fasting and post prandial blood glucose levels, blood pressure, waist circumference, weight and height were measured. MS was diagnosed using the National Cholesterol Education Program (NCEP - ATP III) criteria. RESULTS: Mean weight, body mass index, waist circumference, blood glucose and triglycerides were significantly higher in the study group and HDL cholesterol was significantly lower in the control group. CONCLUSIONS: These results suggest a significant relationship between GD and the occurrence of MS.
BACKGROUND: The metabolic syndrome (MS) is associated to a significant increase in the risk of diabetes, coronary heart disease and stroke, resulting in a 5-fold increase of the cardiovascular death rate. AIM: To determine the relationship between gestational diabetes (GD) and the development of MS at the end of puerperal period. PATIENTS AND METHODS: We conducted a case-control study in the Curanilahue Hospital, in southern Chile, including 58 women with GD during their pregnancy, studied in day 42 of their puerperal period (study group) and 58 puerperal women from the same hospital, who had a physiological pregnancy (control group). Triglycerides, HDL cholesterol, fasting and post prandial blood glucose levels, blood pressure, waist circumference, weight and height were measured. MS was diagnosed using the National Cholesterol Education Program (NCEP - ATP III) criteria. RESULTS: Mean weight, body mass index, waist circumference, blood glucose and triglycerides were significantly higher in the study group and HDL cholesterol was significantly lower in the control group. CONCLUSIONS: These results suggest a significant relationship between GD and the occurrence of MS.