OBJECTIVE: The purpose of our study was to show the usefulness of nongated low-dose chest CT for coronary screening by comparing the results of coronary artery calcium measurement with that of dedicated calcium-scoring CT. MATERIALS AND METHODS: One hundred twenty-eight consecutive participants (all men; mean age, 52 +/- 7 years) underwent low-dose chest CT and calcium-scoring CT with prospective ECG gating using 40-MDCT. Low-dose chest CT volume data were reconstructed as 25-cm field of view and three slice thicknesses: 1, 2.5, and 5 mm. For each examination, the lesion area, Agatston calcium score, and calcium mass were measured at 90- and 130-H thresholds. All measurements (130-H threshold) from the calcium-scoring CT were used as reference standards. Spearman's correlation test was used to compare the results. RESULTS: Among the low-dose chest CT examinations, sensitivity was best determined with a 1-mm slice thickness at 130 H and 2.5-mm slice thickness at 90 H. Specificity was best determined with a 5-mm slice thickness at 130 H. Accuracy (90%) was best determined with a 2.5-mm slice thickness at 130 H. Of all protocols, calcium area, score, and mass from a 2.5-mm slice thickness at 130 H correlated best with the reference results (r = 0.89 for all three criteria). CONCLUSION: Using a low radiation dose and nongated MDCT, we can detect coronary artery calcium and obtain results comparable to those obtained with dedicated calcium-scoring CT that uses a higher dose and ECG gating.
OBJECTIVE: The purpose of our study was to show the usefulness of nongated low-dose chest CT for coronary screening by comparing the results of coronary artery calcium measurement with that of dedicated calcium-scoring CT. MATERIALS AND METHODS: One hundred twenty-eight consecutive participants (all men; mean age, 52 +/- 7 years) underwent low-dose chest CT and calcium-scoring CT with prospective ECG gating using 40-MDCT. Low-dose chest CT volume data were reconstructed as 25-cm field of view and three slice thicknesses: 1, 2.5, and 5 mm. For each examination, the lesion area, Agatston calcium score, and calcium mass were measured at 90- and 130-H thresholds. All measurements (130-H threshold) from the calcium-scoring CT were used as reference standards. Spearman's correlation test was used to compare the results. RESULTS: Among the low-dose chest CT examinations, sensitivity was best determined with a 1-mm slice thickness at 130 H and 2.5-mm slice thickness at 90 H. Specificity was best determined with a 5-mm slice thickness at 130 H. Accuracy (90%) was best determined with a 2.5-mm slice thickness at 130 H. Of all protocols, calcium area, score, and mass from a 2.5-mm slice thickness at 130 H correlated best with the reference results (r = 0.89 for all three criteria). CONCLUSION: Using a low radiation dose and nongated MDCT, we can detect coronary artery calcium and obtain results comparable to those obtained with dedicated calcium-scoring CT that uses a higher dose and ECG gating.
Authors: Luckmini Liyanage; Nam Ju Lee; Tessa Cook; Howard C Herrmann; Dinesh Jagasia; Harold Litt; Yuchi Han Journal: Int J Cardiovasc Imaging Date: 2015-08-29 Impact factor: 2.357
Authors: Divay Chandra; James Londino; Shaun Alexander; Joseph S Bednash; Yingze Zhang; Robert M Friedlander; Grant Daskivich; Diane L Carlisle; William R Lariviere; Ana Carolina Igami Nakassa; Mark Ross; Claudette St Croix; Toru Nyunoya; Frank Sciurba; Bill Chen; Rama K Mallampalli Journal: J Mol Cell Cardiol Date: 2018-11-16 Impact factor: 5.000
Authors: Matthew J Budoff; Khurram Nasir; Gregory L Kinney; John E Hokanson; R Graham Barr; Robert Steiner; Hrudaya Nath; Carmen Lopez-Garcia; Jennifer Black-Shinn; Richard Casaburi Journal: J Cardiovasc Comput Tomogr Date: 2010-11-22
Authors: Yoon Kyung Kim; Yon Mi Sung; So Hyun Cho; Young Nam Park; Hye-Young Choi Journal: Int J Cardiovasc Imaging Date: 2014-08-02 Impact factor: 2.357