Literature DB >> 18355848

Is long-term bladder deterioration inevitable following successful isolated bladder outlet procedures in children with neuropathic bladder dysfunction?

Sumit Dave1, Joao L Pippi Salle, Armando J Lorenzo, Luis H P Braga, Maria Helena Peralta-Del Valle, Darius Bägli, Antoine E Khoury.   

Abstract

PURPOSE: Bladder decompensation is well described following artificial urinary sphincter implantation in neurogenic bladders. We evaluated the long-term results of various bladder outlet procedures in a subset of patients with neurogenic bladder and isolated outlet deficiency.
MATERIALS AND METHODS: We retrospectively reviewed the charts of 15 consecutive patients who underwent bladder outlet procedures during a 10-year period for urinary incontinence associated with neuropathic bladder dysfunction. Postoperative success was defined as a dry interval of at least 4 hours.
RESULTS: Preoperative evaluation showed a smooth bladder in 11 patients with vesicoureteral reflux and hydronephrosis in 2. Using the minimal acceptable capacity for age, mean percent expected bladder capacity for age was 89% +/- 25%, capacity below 20 cm H(2)O was 81% and capacity below 30 cm H(2)O was 89%. Mean preoperative expected capacity for age was 60% +/- 18%. Mean postoperative followup was 11.2 years. Postoperatively, 11 patients achieved initial dryness but 9 subsequently presented with recurrent incontinence and 2 presented with upper tract deterioration. Four cases failed the initial bladder outlet procedure. Salvage procedures included augmentation cystoplasty in all 15 patients, combined with repeat bladder outlet procedure in 4 and bladder neck closure in 2. Mean time to augmentation cystoplasty was 39.6 +/- 28 months.
CONCLUSIONS: Isolated bladder outlet procedures for neurogenic incontinence portend a poor long-term outcome, requiring augmentation cystoplasty despite the use of anticholinergic medications and strict followup. Preoperative urodynamic evaluation does not predict the need or timing from the initial bladder outlet procedure for future augmentation cystoplasty.

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Year:  2008        PMID: 18355848     DOI: 10.1016/j.juro.2008.01.063

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  5 in total

Review 1.  Prevention of chronic kidney disease in spina bifida.

Authors:  Guido Filler; Mireille Gharib; Shelley Casier; Petra Lödige; Jochen H H Ehrich; Sumit Dave
Journal:  Int Urol Nephrol       Date:  2011-01-13       Impact factor: 2.370

2.  [Artificial sphincter for the treatment of incontinence].

Authors:  N Djakovic; J Huber; J Nyarangi-Dix; M Hohenfellner
Journal:  Urologe A       Date:  2010-04       Impact factor: 0.639

3.  Potential impact of epidural stimulation on neurogenic bladder function and the value of urodynamic studies throughout usage.

Authors:  Lisa Beck; Daniel Veith; Margaux Linde; Megan Gill; Jonathan Calvert; Peter Grahn; Kristin Garlanger; Douglas Husmann; Igor Lavrov; Dimitry Sayenko; Jeffrey Strommen; Kendall Lee; Kristin Zhao
Journal:  J Spinal Cord Med       Date:  2021-07       Impact factor: 2.040

Review 4.  Recent Advances in Urinary Tract Reconstruction for Neuropathic Bladder in Children.

Authors:  Roberto I Lopes; Armando Lorenzo
Journal:  F1000Res       Date:  2016-02-22

Review 5.  The Management of the Pediatric Neurogenic Bladder.

Authors:  Renea M Sturm; Earl Y Cheng
Journal:  Curr Bladder Dysfunct Rep       Date:  2016-07-02
  5 in total

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