| Literature DB >> 18355717 |
Junichi Tanaka1, J Craig Blain, John S Allingham.
Abstract
Actin-binding marine macrolides exhibit significant structural and functional diversity. In this issue, Perrins et al. demonstrate that a long stereochemically conserved aliphatic side chain, known as the "tail", found in many of these compounds is the functional determinant of cytotoxicity (Perrins et al., 2008).Entities:
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Year: 2008 PMID: 18355717 DOI: 10.1016/j.chembiol.2008.02.012
Source DB: PubMed Journal: Chem Biol ISSN: 1074-5521