Literature DB >> 18355717

Actin-binding toxin "tail" wags the dog.

Junichi Tanaka1, J Craig Blain, John S Allingham.   

Abstract

Actin-binding marine macrolides exhibit significant structural and functional diversity. In this issue, Perrins et al. demonstrate that a long stereochemically conserved aliphatic side chain, known as the "tail", found in many of these compounds is the functional determinant of cytotoxicity (Perrins et al., 2008).

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Year:  2008        PMID: 18355717     DOI: 10.1016/j.chembiol.2008.02.012

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  2 in total

1.  Studies on the Synthesis of Reidispongiolide A: Stereoselective Synthesis of the C(22)-C(36) Fragment.

Authors:  Maben Ying; William R Roush
Journal:  Tetrahedron       Date:  2011-12-30       Impact factor: 2.457

2.  Molecular docking and QSAR of aplyronine A and analogues: potent inhibitors of actin.

Authors:  Abrar Hussain; James L Melville; Jonathan D Hirst
Journal:  J Comput Aided Mol Des       Date:  2009-11-05       Impact factor: 3.686

  2 in total

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