| Literature DB >> 18354783 |
Hanife Esengil1, James K Chen.
Abstract
Achieving the potential of zebrafish models in biomedical research is contingent on the development of reverse-genetic resources. This review describes current technologies for genetic perturbations in zebrafish, including an ecdysone receptor-based system that permits conditional transgene expression. Such methodologies promise to enable new zebrafish models for interrogating human physiology and disease.Entities:
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Year: 2008 PMID: 18354783 DOI: 10.1039/b718447f
Source DB: PubMed Journal: Mol Biosyst ISSN: 1742-2051