Literature DB >> 18354721

Lumbar facet joint nerve blocks in managing chronic facet joint pain: one-year follow-up of a randomized, double-blind controlled trial: Clinical Trial NCT00355914.

Laxmaiah Manchikanti1, Vijay Singh, Frank J E Falco, Kimberly A Cash, Vidyasagar Pampati.   

Abstract

BACKGROUND: Lumbar facet joints have been implicated as the source of chronic pain in 15% to 45% of patients with chronic low back pain. Various therapeutic techniques including intraarticular injections, medial branch blocks, and radiofrequency neurotomy of lumbar facet joint nerves have been described in the alleviation of chronic low back pain of facet joint origin.
OBJECTIVE: The study was conducted to determine the clinical effectiveness of therapeutic local anesthetic lumbar facet joint nerve blocks with or without steroid in managing chronic function-limiting low back pain of facet joint origin.
DESIGN: A randomized, double-blind, controlled trial.
SETTING: An interventional pain management setting in the United States.
METHODS: This study included 60 patients in Group I with local anesthetic and 60 patients in Group II with local anesthetic and steroid. The inclusion criteria was based on the positive response to the diagnostic controlled comparative local anesthetic lumbar facet joint blocks. OUTCOME MEASURES: Numeric pain scores, Oswestry Disability Index, opioid intake, and work status. All outcome assessments were performed at baseline, 3 months, 6 months, and 12 months.
RESULTS: Significant improvement with significant pain relief (> 50%) and functional improvement (> 40%) were observed in 82% and 85% in Group I, with significant pain relief in over 82% of the patients and improvement in functional status in 78% of the patients. Based on the results of the present study, it appears that patients may experience significant pain relief 44 to 45 weeks of 1 year, requiring approximately 3 to 4 treatments with an average relief of 15 weeks per episode of treatment.
CONCLUSION: Therapeutic lumbar facet joint nerve blocks, with or without steroid, may provide a management option for chronic function-limiting low back pain of facet joint origin.

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Year:  2008        PMID: 18354721

Source DB:  PubMed          Journal:  Pain Physician        ISSN: 1533-3159            Impact factor:   4.965


  30 in total

Review 1.  The lumbar facet joint: a review of current knowledge: Part II: diagnosis and management.

Authors:  Gerard P Varlotta; Todd R Lefkowitz; Mark Schweitzer; Thomas J Errico; Jeffrey Spivak; John A Bendo; Leon Rybak
Journal:  Skeletal Radiol       Date:  2010-06-26       Impact factor: 2.199

Review 2.  Evidence-based radiology (part 1): Is there sufficient research to support the use of therapeutic injections for the spine and sacroiliac joints?

Authors:  Cynthia Peterson; Juerg Hodler
Journal:  Skeletal Radiol       Date:  2010-01       Impact factor: 2.199

Review 3.  [Neuroablative procedures in pain therapy].

Authors:  V M Tronnier; D Rasche
Journal:  Schmerz       Date:  2009-10       Impact factor: 1.107

Review 4.  Adverse events from diagnostic and therapeutic joint injections: a literature review.

Authors:  Cynthia Peterson; Juerg Hodler
Journal:  Skeletal Radiol       Date:  2009-12-01       Impact factor: 2.199

5.  Topological analyses of time-dependent electronic structures: application to electron-transfers in methionine enkephalin.

Authors:  Julien Pilmé; Eleonora Luppi; Jacqueline Bergès; Chantal Houée-Lévin; Aurélien de la Lande
Journal:  J Mol Model       Date:  2014-07-25       Impact factor: 1.810

6.  Paravertebral spinal injection for the treatment of patients with degenerative facet osteoarthropathy: Evidence of motor performance improvements based on objective assessments.

Authors:  Nima Toosizadeh; Homayoon Harati; Tzu-Chuan Yen; Cindy Fastje; Jane Mohler; Bijan Najafi; Michael Dohm
Journal:  Clin Biomech (Bristol, Avon)       Date:  2016-10-11       Impact factor: 2.063

Review 7.  Responder analyses in randomised controlled trials for chronic low back pain: an overview of currently used methods.

Authors:  Nicholas Henschke; Annefloor van Enst; Robert Froud; Raymond W G Ostelo
Journal:  Eur Spine J       Date:  2014-01-14       Impact factor: 3.134

8.  Consensus practice guidelines on interventions for lumbar facet joint pain from a multispecialty, international working group.

Authors:  Steven P Cohen; Arun Bhaskar; Anuj Bhatia; Asokumar Buvanendran; Tim Deer; Shuchita Garg; W Michael Hooten; Robert W Hurley; David J Kennedy; Brian C McLean; Jee Youn Moon; Samer Narouze; Sanjog Pangarkar; David Anthony Provenzano; Richard Rauck; B Todd Sitzman; Matthew Smuck; Jan van Zundert; Kevin Vorenkamp; Mark S Wallace; Zirong Zhao
Journal:  Reg Anesth Pain Med       Date:  2020-04-03       Impact factor: 6.288

9.  Evaluation of lumbar facet joint nerve blocks in managing chronic low back pain: a randomized, double-blind, controlled trial with a 2-year follow-up.

Authors:  Laxmaiah Manchikanti; Vijay Singh; Frank J E Falco; Kimberly A Cash; Vidyasagar Pampati
Journal:  Int J Med Sci       Date:  2010-05-28       Impact factor: 3.738

Review 10.  Injection therapy and denervation procedures for chronic low-back pain: a systematic review.

Authors:  Nicholas Henschke; Ton Kuijpers; Sidney M Rubinstein; Marienke van Middelkoop; Raymond Ostelo; Arianne Verhagen; Bart W Koes; Maurits W van Tulder
Journal:  Eur Spine J       Date:  2010-04-29       Impact factor: 3.134

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