| Literature DB >> 1835452 |
H M Inskip1, A J Hall, J Chotard, F Loik, H Whittle.
Abstract
Data on over a thousand Gambian children have been analysed to examine factors influencing their antibody levels following immunization with hepatitis B vaccine administered during the first year of life. The dominant effect was the time between the last dose of vaccine and taking the blood sample. There was considerable variation in vaccine response by area of residence which could not be explained by any other factor. The hepatitis B surface antigen (HBsAg) status of the mother and the age at vaccination did not appear to have an effect, but there was some indication that a delay in receiving the second dose of vaccine led to a marginally lower response.Entities:
Keywords: Africa; Africa South Of The Sahara; Age Factors; Antibodies; Antigen-antibody Reactions; Biology; Cohort Analysis; Cultural Background; Delivery Of Health Care; Demographic Factors; Developing Countries; Diseases; English Speaking Africa; Examinations And Diagnoses; Gambia; Geographic Factors; Health; Health Services; Hematologic Tests; Immunity; Immunization; Immunologic Factors; Infant; Laboratory Examinations And Diagnoses; Laboratory Procedures; Locale; Methodological Studies; Physiology; Population; Population Characteristics; Population Dynamics; Primary Health Care; Research Methodology; Residence Characteristics; Spatial Distribution; Time Factors; Tribes; Vaccination; Viral Diseases; Western Africa; Youth
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Year: 1991 PMID： 1835452 DOI： 10.1093/ije/20.3.764
Source DB: PubMed Journal: Int J Epidemiol ISSN： 0300-5771 Impact factor: 7.196