Literature DB >> 18354417

The distinctive biology of cancer in adolescents and young adults.

Archie Bleyer1, Ronald Barr, Brandon Hayes-Lattin, David Thomas, Chad Ellis, Barry Anderson.   

Abstract

One explanation for the relative lack of progress in treating cancer in adolescents and young adults is that the biology of malignant diseases in this age group is different than in younger and older persons, not only in the spectrum of cancers but also within individual cancer types and within the patient (host). Molecular, epidemiological and therapeutic outcome comparisons offer clues to this distinctiveness in most of the common cancers of adolescents and young adults. Translational and clinical research should not assume that the biology of cancers and patients is the same as in other age groups, and treatment strategies should be tailored to the differences.

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Mesh：

Year:  2008        PMID： 18354417     DOI： 10.1038/nrc2349

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  194 in total

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Review 2.  Canadian adolescents and young adults with cancer: opportunity to improve coordination and level of care.

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4.  Cancer experiences and health-related quality of life among racial and ethnic minority survivors of young adult cancer: a mixed methods study.

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Review 5.  Long-term complications in adolescent and young adult leukemia survivors.

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6.  A Process for Change in the Care of Adolescents and Young Adults with Cancer in Canada. "Moving to Action": The Second Canadian International Workshop. International Perspectives on AYAO, Part 1.

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7.  Rethinking Adherence: A Proposal for a New Approach to Risk Assessment.

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Review 9.  Reproductive health in the adolescent and young adult cancer patient: an innovative training program for oncology nurses.

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