Literature DB >> 18353645

Increasing permeability of phospholipid bilayer membranes to alanine with synthetic alpha-aminophosphonate carriers.

Delia C Danila1, Xinyan Wang, Heather Hubble, Igor S Antipin, Eugene Pinkhassik.   

Abstract

A series of aminophosphonates was synthesized, and their ability to carry alanine, a model hydrophilic molecule, across phospholipid bilayer membranes was evaluated. Aminophosphonates facilitate the membrane transport at moderate rates, which make them a suitable platform for the design of carriers for continuous drug release devices.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18353645     DOI: 10.1016/j.bmcl.2008.02.081

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  3 in total

1.  Asymmetric hydrophosphylation of chiral N-phosphonyl imines provides an efficient approach to chiral α-amino phosphonates.

Authors:  Parminder Kaur; Walter Wever; Trideep Rajale; Guigen Li
Journal:  Chem Biol Drug Des       Date:  2010-10       Impact factor: 2.817

2.  Design, Synthesis, and Antiviral Activity of Novel Ribonucleosides of 1,2,3-Triazolylbenzyl-aminophosphonates.

Authors:  Abdelaaziz Ouahrouch; Moha Taourirte; Dominique Schols; Robert Snoeck; Graciela Andrei; Joachim W Engels; Hassan B Lazrek
Journal:  Arch Pharm (Weinheim)       Date:  2015-11-17       Impact factor: 3.751

Review 3.  The Kabachnik-Fields reaction: mechanism and synthetic use.

Authors:  György Keglevich; Erika Bálint
Journal:  Molecules       Date:  2012-11-01       Impact factor: 4.411

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.