| Literature DB >> 18353641 |
Cyrille Tomassi1, Van Nhien Albert Nguyen, José Marco-Contelles, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Elena Soriano, Denis Postel.
Abstract
The synthesis and the biological evaluation of the anti-HIV-1 activity of TSAO-Boc(3)T (8) are described. The computational analysis showed that the N-3 Boc group promotes new interactions in the binding site of the enzyme leading to a good inhibitory activity.Entities:
Mesh：
Substances：
Year: 2008 PMID： 18353641 DOI： 10.1016/j.bmcl.2008.03.010
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823