OBJECTIVE: To propose a new theory describing the development of the fallopian tube fimbria. DESIGN: Case series report. SETTING: Metropolitan tertiary care children's hospital. PATIENT(S): Two girls, aged 12 and 20 years, who presented with pelvic pain. INTERVENTION(S): Magnetic resonance imaging, laparoscopy with salpingectomy, and pathologic analysis. MAIN OUTCOME MEASURE(S): Description of a novel theory regarding the embryologic development of the fallopian tube and its fimbria. RESULT(S): In two non-sexually active girls the cause of their pelvic pain was found to be a hydrosalpinx associated with a discontinuous fallopian tube in which the fimbriated end did not directly communicate with the remainder of the fallopian tube. CONCLUSION(S): The two cases of pure congenital fallopian tube atresia, the presence of fimbriae in patients with müllerian (uterine, cervical, and vaginal) agenesis, and the role of the fimbria in ovarian-like and peritoneal cancers, support a novel hypothesis that the fimbria of the fallopian tube may arise separately from the rest of the tube.
OBJECTIVE: To propose a new theory describing the development of the fallopian tube fimbria. DESIGN: Case series report. SETTING: Metropolitan tertiary care children's hospital. PATIENT(S): Two girls, aged 12 and 20 years, who presented with pelvic pain. INTERVENTION(S): Magnetic resonance imaging, laparoscopy with salpingectomy, and pathologic analysis. MAIN OUTCOME MEASURE(S): Description of a novel theory regarding the embryologic development of the fallopian tube and its fimbria. RESULT(S): In two non-sexually active girls the cause of their pelvic pain was found to be a hydrosalpinx associated with a discontinuous fallopian tube in which the fimbriated end did not directly communicate with the remainder of the fallopian tube. CONCLUSION(S): The two cases of pure congenital fallopian tube atresia, the presence of fimbriae in patients with müllerian (uterine, cervical, and vaginal) agenesis, and the role of the fimbria in ovarian-like and peritoneal cancers, support a novel hypothesis that the fimbria of the fallopian tube may arise separately from the rest of the tube.
Authors: Anthony N Karnezis; Kathleen R Cho; C Blake Gilks; Celeste Leigh Pearce; David G Huntsman Journal: Nat Rev Cancer Date: 2016-11-25 Impact factor: 60.716
Authors: Kay J Park; Vance Broach; Dennis S Chi; Irina Linkov; Frank Z Stanczyk; Prusha Patel; Anjali Jotwani; Celeste Leigh Pearce; Malcolm C Pike; Noah D Kauff Journal: Cancer Epidemiol Biomarkers Prev Date: 2022-09-02 Impact factor: 4.090
Authors: Christopher P Crum; Michael Herfs; Gang Ning; Jonathan G Bijron; Brooke E Howitt; Cynthia A Jimenez; Suchanan Hanamornroongruang; Frank D McKeon; Wa Xian Journal: J Pathol Date: 2013-12 Impact factor: 7.996