Literature DB >> 18351912

Identifying network communities with a high resolution.

Jianhua Ruan1, Weixiong Zhang.   

Abstract

Community structure is an important property of complex networks. The automatic discovery of such structure is a fundamental task in many disciplines, including sociology, biology, engineering, and computer science. Recently, several community discovery algorithms have been proposed based on the optimization of a modularity function (Q) . However, the problem of modularity optimization is NP-hard and the existing approaches often suffer from a prohibitively long running time or poor quality. Furthermore, it has been recently pointed out that algorithms based on optimizing Q will have a resolution limit; i.e., communities below a certain scale may not be detected. In this research, we first propose an efficient heuristic algorithm QCUT, which combines spectral graph partitioning and local search to optimize Q . Using both synthetic and real networks, we show that QCUT can find higher modularities and is more scalable than the existing algorithms. Furthermore, using QCUT as an essential component, we propose a recursive algorithm HQCUT to solve the resolution limit problem. We show that HQCUT can successfully detect communities at a much finer scale or with a higher accuracy than the existing algorithms. We also discuss two possible reasons that can cause the resolution limit problem and provide a method to distinguish them. Finally, we apply QCUT and HQCUT to study a protein-protein interaction network and show that the combination of the two algorithms can reveal interesting biological results that may be otherwise undetected.

Year:  2008        PMID: 18351912     DOI: 10.1103/PhysRevE.77.016104

Source DB:  PubMed          Journal:  Phys Rev E Stat Nonlin Soft Matter Phys        ISSN: 1539-3755


  46 in total

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Authors:  Qawi K Telesford; Sean L Simpson; Jonathan H Burdette; Satoru Hayasaka; Paul J Laurienti
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2.  Assessing the consistency of community structure in complex networks.

Authors:  Matthew Steen; Satoru Hayasaka; Karen Joyce; Paul Laurienti
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2011-07-26

3.  Connectivity patterns during music listening: Evidence for action-based processing in musicians.

Authors:  Vinoo Alluri; Petri Toiviainen; Iballa Burunat; Marina Kliuchko; Peter Vuust; Elvira Brattico
Journal:  Hum Brain Mapp       Date:  2017-03-28       Impact factor: 5.038

4.  Intrinsic functional architecture of the macaque dorsal and ventral lateral frontal cortex.

Authors:  Alexandros Goulas; Peter Stiers; R Matthew Hutchison; Stefan Everling; Michael Petrides; Daniel S Margulies
Journal:  J Neurophysiol       Date:  2016-12-21       Impact factor: 2.714

5.  A novel link prediction algorithm for reconstructing protein-protein interaction networks by topological similarity.

Authors:  Chengwei Lei; Jianhua Ruan
Journal:  Bioinformatics       Date:  2012-12-11       Impact factor: 6.937

6.  A general co-expression network-based approach to gene expression analysis: comparison and applications.

Authors:  Jianhua Ruan; Angela K Dean; Weixiong Zhang
Journal:  BMC Syst Biol       Date:  2010-02-02

7.  A new measure of centrality for brain networks.

Authors:  Karen E Joyce; Paul J Laurienti; Jonathan H Burdette; Satoru Hayasaka
Journal:  PLoS One       Date:  2010-08-16       Impact factor: 3.240

8.  Age-related differences in advantageous decision making are associated with distinct differences in functional community structure.

Authors:  Malaak Nasser Moussa; Michael J Wesley; Linda J Porrino; Satoru Hayasaka; Antoine Bechara; Jonathan H Burdette; Paul J Laurienti
Journal:  Brain Connect       Date:  2014-04-04

9.  A systems biology approach to the identification and analysis of transcriptional regulatory networks in osteocytes.

Authors:  Angela K Dean; Stephen E Harris; Ivo Kalajzic; Jianhua Ruan
Journal:  BMC Bioinformatics       Date:  2009-09-17       Impact factor: 3.169

10.  Variations in the transcriptome of Alzheimer's disease reveal molecular networks involved in cardiovascular diseases.

Authors:  Monika Ray; Jianhua Ruan; Weixiong Zhang
Journal:  Genome Biol       Date:  2008-10-08       Impact factor: 13.583

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