Literature DB >> 18350207

'Look and Lletz'--a Chris Hani Baragwanath Hospital experience.

Y Adam1, C J van Gelderen, K Newell.   

Abstract

OBJECTIVES: An audit was undertaken of a 'colposcopy and treatment' clinic between April 2003 and December 2006, to determine: (i) the frequency of overtreatment with Papanicolaou smear on its own, colposcopy on its own or a combination of the two methods; (ii) differences in overtreatment between patients who are HIV positive and those who are HIV negative; and (iii) the short-term complications of Lletz (large loop excision of the transformation zone) at this clinic.
DESIGN: An analysis of the data from the colposcopy clinic database of patients, who were referred according to national guidelines.
SETTING: Patients who are referred to Chris Hani Baragwanath Hospital.
RESULTS: Normal histology was found in 1.3% of patients, and cervical intraepithelial neoplasia (CIN)1 or human papillomavirus (HPV) in 8.4%. The overall complication rate was 3%.
CONCLUSION: The high loss to follow-up and the low early complication rate together with an acceptable overtreatment rate make this a justifiable approach in our situation. HIV-negative women were more likely to be overtreated than HIV-positive patients(p=0.03).

Entities:  

Mesh:

Year:  2008        PMID: 18350207

Source DB:  PubMed          Journal:  S Afr Med J


  5 in total

1.  Progression and regression of premalignant cervical lesions in HIV-infected women from Soweto: a prospective cohort.

Authors:  Tanvier Omar; Sheree Schwartz; Colleen Hanrahan; Tebogo Modisenyane; Nkeko Tshabangu; Jonathan E Golub; James A McIntyre; Glenda E Gray; Lerato Mohapi; Neil A Martinson
Journal:  AIDS       Date:  2011-01-02       Impact factor: 4.177

2.  Long-term cumulative incidence of cervical intraepithelial neoplasia grade 3 or worse after abnormal cytology: impact of HIV infection.

Authors:  L Stewart Massad; Christopher B Pierce; Howard Minkoff; D Heather Watts; Teresa M Darragh; Lorraine Sanchez-Keeland; Rodney L Wright; Christine Colie; Gypsyamber D'Souza
Journal:  Int J Cancer       Date:  2013-10-29       Impact factor: 7.396

3.  See-and-treat approaches to cervical cancer prevention for HIV-infected women.

Authors:  Carla J Chibwesha; Susan Cu-Uvin
Journal:  Curr HIV/AIDS Rep       Date:  2011-09       Impact factor: 5.071

4.  Predictors of persistent cytologic abnormalities after treatment of cervical intraepithelial neoplasia in Soweto, South Africa: a cohort study in a HIV high prevalence population.

Authors:  Yasmin Adam; Cyril J van Gelderen; Guy de Bruyn; James A McIntyre; Diane A Turton; Neil A Martinson
Journal:  BMC Cancer       Date:  2008-07-25       Impact factor: 4.430

Review 5.  Cervical cancer prevention and treatment research in Africa: a systematic review from a public health perspective.

Authors:  Sarah Finocchario-Kessler; Catherine Wexler; May Maloba; Natabhona Mabachi; Florence Ndikum-Moffor; Elizabeth Bukusi
Journal:  BMC Womens Health       Date:  2016-06-04       Impact factor: 2.809

  5 in total

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