Literature DB >> 1834949

Molecular cloning and characterization of the rat NMDA receptor.

K Moriyoshi1, M Masu, T Ishii, R Shigemoto, N Mizuno, S Nakanishi.   

Abstract

A complementary DNA encoding the rat NMDA receptor has been cloned and characterized. The single protein encoded by the cDNA forms a receptor-channel complex that has electrophysiological and pharmacological properties characteristic of the NMDA receptor. This protein has a significant sequence similarity to the AMPA/kainate receptors and contains four putative transmembrane segments following a large extracellular domain. The NMDA receptor messenger RNA is expressed in neuronal cells throughout the brain regions, particularly in the hippocampus, cerebral cortex and cerebellum.

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Year:  1991        PMID： 1834949     DOI： 10.1038/354031a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  290 in total

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2.  Enhanced NMDA receptor activity in retinal inputs to the rat suprachiasmatic nucleus during the subjective night.

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3.  Alternative splicing of the C-terminal domain regulates cell surface expression of the NMDA receptor NR1 subunit.

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Review 4.  Biochemical studies of the structure and function of the N-methyl-D-aspartate subtype of glutamate receptors.

Authors:  A W Dunah; R P Yasuda; J Luo; Y Wang; K L Prybylowski; B B Wolfe
Journal:  Mol Neurobiol       Date:  1999-04       Impact factor: 5.590

5.  Organization of ionotropic glutamate receptors at dendrodendritic synapses in the rat olfactory bulb.

Authors:  M Sassoè-Pognetto; O P Ottersen
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7.  Characterization of the binding of two novel glycine site antagonists to cloned NMDA receptors: evidence for two pharmacological classes of antagonists.

Authors:  B Chopra; P L Chazot; F A Stephenson
Journal:  Br J Pharmacol       Date:  2000-05       Impact factor: 8.739

8.  Telling tails.

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9.  Cyclosporin A induces the opening of a potassium-selective channel in higher plant mitochondria.

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Journal:  J Bioenerg Biomembr       Date:  2001-04       Impact factor: 2.945

10.  An NMDA receptor signaling complex with protein phosphatase 2A.

Authors:  S F Chan; N J Sucher
Journal:  J Neurosci       Date:  2001-10-15       Impact factor: 6.167
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