Literature DB >> 18348947

Grid-added value to address malaria.

V Breton1, N Jacq, V Kasam, M Hofmann-Apitius.   

Abstract

Through this paper, we call for a distributed, Internet-based collaboration to address one of the worst plagues of our present world, malaria. The spirit is a nonproprietary peer-production of information-embedding goods. And we propose to use the grid technology to enable such a worldwide "open-source" like collaboration. The first step toward this vision has been achieved during the summer 2005 on the enabling grids for E-scienceE (EGEE) grid infrastructure where 42 million ligands were docked for a total amount of 80 CPU years in 6 weeks in the quest for new drugs. The impact of this first deployment has significantly raised the interest of the research community so that several laboratories all around the world expressed interest to propose targets for a second large-scale deployment against malaria.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18348947     DOI: 10.1109/TITB.2007.895930

Source DB:  PubMed          Journal:  IEEE Trans Inf Technol Biomed        ISSN: 1089-7771


  1 in total

1.  Specific Targeting of Plant and Apicomplexa Parasite Tubulin through Differential Screening Using In Silico and Assay-Based Approaches.

Authors:  Emmanuelle Soleilhac; Loraine Brillet-Guéguen; Véronique Roussel; Renaud Prudent; Bastien Touquet; Sheena Dass; Samia Aci-Sèche; Vinod Kasam; Caroline Barette; Anne Imberty; Vincent Breton; Marylin Vantard; Dragos Horvath; Cyrille Botté; Isabelle Tardieux; Sylvaine Roy; Eric Maréchal; Laurence Lafanechère
Journal:  Int J Mol Sci       Date:  2018-10-09       Impact factor: 5.923

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.