Biomedicine in Edinburgh, 1887-1920.

This paper examines the scientific work of the Laboratory of the Royal College of Physicians of Edinburgh from its foundation in 1887 to 1920. It looks in particular at the pivotal role of clinical cases in the work of the Laboratory, using the concept of 'triangulation' to analyse how cases served both as objects of scientific knowledge and as sites for articulating and aligning the concerns of medical practitioners and career scientists. It goes on to propose a general model for thinking about the role of cases in scientific knowledge production, based on a rereading of Kuhn as seen through the lens of the sociology of scientific knowledge. It concludes with some general reflections on how this analysis of the work of the Laboratory helps us to rethink the relations between basic and applied medical science in the period before the emergence of modern biomedicine.