Literature DB >> 18347493

Profound hypokalemia: unusual presentation and management in a 12-year-old boy.

Estevan Garcia1, Nader Nakhleh, Donna Simmons, Carl Ramsay.   

Abstract

Hypokalemia is a frequent electrolyte abnormality that rarely requires more than oral supplementation to correct. We describe a case of profound hypokalemia and cardiac arrhythmia requiring unusually large amounts of "bolused" potassium to restore to normal sinus rhythm. Our patient presented with significant dehydration and electrolyte abnormalities after several days of emesis. Most alarming of these findings was a serum potassium level of 1.2 mEq/L. The electrocardiogram showed changes consistent with hypokalemia that rapidly degraded into pulseless ventricular tachycardia. Potassium chloride of 140 mEq was hand-pushed during the resuscitation with return of spontaneous rhythm. The patient was discharge 11 days later in his prearrest state.

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Year:  2008        PMID: 18347493     DOI: 10.1097/PEC.0b013e318166868e

Source DB:  PubMed          Journal:  Pediatr Emerg Care        ISSN: 0749-5161            Impact factor:   1.454


  4 in total

1.  Extracellular K+ concentration controls cell surface density of IKr in rabbit hearts and of the HERG channel in human cell lines.

Authors:  Jun Guo; Hamid Massaeli; Jianmin Xu; Zongchao Jia; Jeffrey T Wigle; Nasrin Mesaeli; Shetuan Zhang
Journal:  J Clin Invest       Date:  2009-08-24       Impact factor: 14.808

2.  Involvement of caveolin in low K+-induced endocytic degradation of cell-surface human ether-a-go-go-related gene (hERG) channels.

Authors:  Hamid Massaeli; Tao Sun; Xian Li; Heidi Shallow; Jimmy Wu; Jianmin Xu; Wentao Li; Christian Hanson; Jun Guo; Shetuan Zhang
Journal:  J Biol Chem       Date:  2010-07-06       Impact factor: 5.157

3.  Endocytic control of ion channel density as a target for cardiovascular disease.

Authors:  Gail A Robertson
Journal:  J Clin Invest       Date:  2009-08-24       Impact factor: 14.808

4.  Suppression of the hERG potassium channel response to premature stimulation by reduction in extracellular potassium concentration.

Authors:  Dario Melgari; Chunyun Du; Aziza El Harchi; Yihong Zhang; Jules C Hancox
Journal:  Physiol Rep       Date:  2014-10-15
  4 in total

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