Literature DB >> 18346781

Changes of serum albumin affinity for aspirin induced by fatty acid.

B Bojko1, A Sułkowska, M Maciazek, J Równicka, F Njau, W W Sułkowski.   

Abstract

Saturated fatty acids such as myristic acid play an important role in the pathogenesis of cardiovascular disorders. Using the quenching fluorescence method we examined the influence of myristate on the changes of transporting protein affinity towards aspirin-the most popular anticoagulant. Our results showed that the presence of the myristic acid alters the stability of the anticoagulant-albumin complex. The ranges of [myristate]/[albumin] molar ratio at which the stability of drug-protein complex increases or decreases were determined. The differences in interaction between ligands and human or bovine serum albumins were identified. The competition in binding of ligands with these albumins was also described.

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Year:  2007        PMID： 18346781     DOI： 10.1016/j.ijbiomac.2007.11.002

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN： 0141-8130            Impact factor:   6.953


  9 in total

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Journal:  Eur J Drug Metab Pharmacokinet       Date:  2016-12       Impact factor: 2.441

2.  Human serum albumin inhibits Abeta fibrillization through a "monomer-competitor" mechanism.

Authors:  Julijana Milojevic; Annie Raditsis; Giuseppe Melacini
Journal:  Biophys J       Date:  2009-11-04       Impact factor: 4.033

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Journal:  Eur Biophys J       Date:  2012-09-18       Impact factor: 1.733

4.  Real-Time Interrogation of Aspirin Reactivity, Biochemistry, and Biodistribution by Hyperpolarized Magnetic Resonance Spectroscopy.

Authors:  Niki M Zacharias; Argentina Ornelas; Jaehyuk Lee; Jingzhe Hu; Jennifer S Davis; Nasir Uddin; Shivanand Pudakalakatti; David G Menter; Jose A Karam; Christopher G Wood; Ernest T Hawk; Scott Kopetz; Eduardo Vilar; Pratip K Bhattacharya; Steven W Millward
Journal:  Angew Chem Int Ed Engl       Date:  2019-02-20       Impact factor: 15.336

5.  Interaction of bioactive coomassie brilliant blue g with protein: insights from spectroscopic methods.

Authors:  Umesha Katrahalli; Shankara Sharanappa Kalanur; Jaladappagari Seetharamappa
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6.  Determination of supplier-to-supplier and lot-to-lot variability in glycation of recombinant human serum albumin expressed in Oryza sativa.

Authors:  Grant E Frahm; Daryl G S Smith; Anita Kane; Barry Lorbetskie; Terry D Cyr; Michel Girard; Michael J W Johnston
Journal:  PLoS One       Date:  2014-10-09       Impact factor: 3.240

7.  In Vitro Investigations of Acetohexamide Binding to Glycated Serum Albumin in the Presence of Fatty Acid.

Authors:  Agnieszka Szkudlarek; Michał Wilk; Małgorzata Maciążek-Jurczyk
Journal:  Molecules       Date:  2020-05-17       Impact factor: 4.411

8.  Use of spectroscopic, zeta potential and molecular dynamic techniques to study the interaction between human holo-transferrin and two antagonist drugs: comparison of binary and ternary systems.

Authors:  Mona Kabiri; Zeinab Amiri-Tehranizadeh; Ali Baratian; Mohammad Reza Saberi; Jamshidkhan Chamani
Journal:  Molecules       Date:  2012-03-12       Impact factor: 4.411

9.  A molecular dynamics approach to ligand-receptor interaction in the aspirin-human serum albumin complex.

Authors:  H Ariel Alvarez; Andrés N McCarthy; J Raúl Grigera
Journal:  J Biophys       Date:  2012-11-21
  9 in total

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