OBJECTIVE: Mortality of 40% to 86% and good outcomes in only 13% to 21% of patients beg for treatment options for basilar occlusion. This study determined outcomes of patients with vertebrobasilar occlusion treated with mechanical embolus removal in cerebral ischemia (MERCI) retriever mechanical thrombectomy. METHODS: Patients with vertebrobasilar occlusion in the MERCI and Multi-MERCI trials received treatment up to 8 hours after symptom onset. Recanalization was determined after retriever use and adjunctive therapy. Mortality and good outcomes, modified Rankin scale score 0-3, were determined at 90 days in patients who were recanalized and not recanalized. RESULTS: Recanalization occurred in 21 of 27 (78%) patients. Mortality was 44% and good outcomes were seen in 41%. Patients with recanalization tended to have better outcomes than those without. CONCLUSIONS: Outcomes in patients with vertebrobasilar occlusions treated with the MERCI retriever compared favorably with natural history reports and tended to be better in those patients with recanalization.
OBJECTIVE: Mortality of 40% to 86% and good outcomes in only 13% to 21% of patients beg for treatment options for basilar occlusion. This study determined outcomes of patients with vertebrobasilar occlusion treated with mechanical embolus removal in cerebral ischemia (MERCI) retriever mechanical thrombectomy. METHODS:Patients with vertebrobasilar occlusion in the MERCI and Multi-MERCI trials received treatment up to 8 hours after symptom onset. Recanalization was determined after retriever use and adjunctive therapy. Mortality and good outcomes, modified Rankin scale score 0-3, were determined at 90 days in patients who were recanalized and not recanalized. RESULTS: Recanalization occurred in 21 of 27 (78%) patients. Mortality was 44% and good outcomes were seen in 41%. Patients with recanalization tended to have better outcomes than those without. CONCLUSIONS: Outcomes in patients with vertebrobasilar occlusions treated with the MERCI retriever compared favorably with natural history reports and tended to be better in those patients with recanalization.
Authors: P Mordasini; C Brekenfeld; J V Byrne; U Fischer; M Arnold; M R Heldner; R Lüdi; H P Mattle; G Schroth; J Gralla Journal: AJNR Am J Neuroradiol Date: 2012-06-21 Impact factor: 3.825
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Authors: M Espinosa de Rueda; G Parrilla; J Zamarro; B García-Villalba; F Hernández; A Moreno Journal: AJNR Am J Neuroradiol Date: 2012-11-01 Impact factor: 3.825
Authors: Y-I Eom; Y-H Hwang; J M Hong; J W Choi; Y C Lim; D-H Kang; Y-W Kim; Y-S Kim; S Y Kim; J S Lee Journal: AJNR Am J Neuroradiol Date: 2014-07-17 Impact factor: 3.825
Authors: I Mourand; H Brunel; V Costalat; C Riquelme; K Lobotesis; D Milhaud; C Héroum; C Arquizan; M Moynier; A Bonafé Journal: AJNR Am J Neuroradiol Date: 2011-07-28 Impact factor: 3.825
Authors: I Mourand; P Machi; E Nogué; C Arquizan; V Costalat; M-C Picot; A Bonafé; D Milhaud Journal: AJNR Am J Neuroradiol Date: 2014-02-13 Impact factor: 3.825