Literature DB >> 18345497

Molecular determinants of ligand-directed signaling for the histamine H1 receptor.

R G Booth1, L Fang, A Wilczynski, S Sivendren, Z Sun, S Travers, M Bruysters, K Sansuk, R Leurs.   

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Year:  2008        PMID： 18345497      PMCID： PMC3712339          DOI： 10.1007/s00011-007-0621-3

Source DB:  PubMed          Journal:  Inflamm Res        ISSN： 1023-3830            Impact factor:   4.575


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  7 in total

1.  Role of PKA and PKC in histamine H1 receptor-mediated activation of catecholamine neurotransmitter synthesis.

Authors:  Nader H Moniri; Raymond G Booth
Journal:  Neurosci Lett       Date:  2006-09-15       Impact factor: 3.046

2.  A novel phenylaminotetralin (PAT) recognizes histamine H1 receptors and stimulates dopamine synthesis in vivo in rat brain.

Authors:  N Y Choksi; W B Nix; S D Wyrick; R G Booth
Journal:  Brain Res       Date:  2000-01-03       Impact factor: 3.252

3.  Linking agonist binding to histamine H1 receptor activation.

Authors:  Aldo Jongejan; Martijn Bruysters; Juan A Ballesteros; Eric Haaksma; Remko A Bakker; Leonardo Pardo; Rob Leurs
Journal:  Nat Chem Biol       Date:  2005-06-19       Impact factor: 15.040

4.  Site-directed mutagenesis of the histamine H1 receptor: roles of aspartic acid107, asparagine198 and threonine194.

Authors:  K Ohta; H Hayashi; H Mizuguchi; H Kagamiyama; K Fujimoto; H Fukui
Journal:  Biochem Biophys Res Commun       Date:  1994-09-15       Impact factor: 3.575

5.  Modelling and mutation studies on the histamine H1-receptor agonist binding site reveal different binding modes for H1-agonists: Asp116 (TM3) has a constitutive role in receptor stimulation.

Authors:  A M ter Laak; H Timmerman; R Leurs; P H Nederkoorn; M J Smit; G M Donné-Op den Kelder
Journal:  J Comput Aided Mol Des       Date:  1995-08       Impact factor: 3.686

6.  Mutational analysis of the histamine H1-receptor binding pocket of histaprodifens.

Authors:  Martijn Bruysters; Heinz H Pertz; Aloys Teunissen; Remko A Bakker; Michel Gillard; Pierre Chatelain; Walter Schunack; Henk Timmerman; Rob Leurs
Journal:  Eur J Pharmacol       Date:  2004-03-08       Impact factor: 4.432

7.  Ligand-directed functional heterogeneity of histamine H1 receptors: novel dual-function ligands selectively activate and block H1-mediated phospholipase C and adenylyl cyclase signaling.

Authors:  Nader H Moniri; Dawn Covington-Strachan; Raymond G Booth
Journal:  J Pharmacol Exp Ther       Date:  2004-05-28       Impact factor: 4.030
  7 in total
  5 in total

1.  Novel 4-substituted-N,N-dimethyltetrahydronaphthalen-2-amines: synthesis, affinity, and in silico docking studies at serotonin 5-HT2-type and histamine H1 G protein-coupled receptors.

Authors:  Rajeev Sakhuja; Krishnakanth Kondabolu; Tania Córdova-Sintjago; Sean Travers; Adam S Vincek; Myong Sang Kim; Khalil A Abboud; Lijuan Fang; Zhuming Sun; Clinton E Canal; Raymond G Booth
Journal:  Bioorg Med Chem       Date:  2015-02-07       Impact factor: 3.641

Review 2.  Migraine signaling pathways: amino acid metabolites that regulate migraine and predispose migraineurs to headache.

Authors:  Roger Gregory Biringer
Journal:  Mol Cell Biochem       Date:  2022-04-28       Impact factor: 3.842

3.  Aromatic interactions impact ligand binding and function at serotonin 5-HT2C G protein-coupled receptors: Receptor homology modeling, ligand docking, and molecular dynamics results validated by experimental studies.

Authors:  Tania Córdova-Sintjago; Nancy Villa; Lijuan Fang; Raymond G Booth
Journal:  Mol Phys       Date:  2014-01-01       Impact factor: 1.962

4.  Molecular determinants of ligand binding at the human histamine H1 receptor: Site-directed mutagenesis results analyzed with ligand docking and molecular dynamics studies at H1 homology and crystal structure models.

Authors:  Tania C Cordova-Sintjago; Lijuan Fang; Martijn Bruysters; Rob Leurs; Raymond G Booth
Journal:  J Chem Pharm Res       Date:  2012-06

5.  Molecular Determinants for Ligand Binding at Serotonin 5-HT2A and 5-HT2C GPCRs: Experimental Affinity Results Analyzed by Molecular Modeling and Ligand Docking Studies.

Authors:  Tania Córdova-Sintjago; Rajeev Sakhuja; Krishnakanth Kondabolu; Clinton E Canal; Raymond G Booth
Journal:  Int J Quantum Chem       Date:  2012-12-15       Impact factor: 2.444
  5 in total

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