Literature DB >> 18345433

Total agenesis of the corpus callosum in a patient with childhood-onset schizophrenia.

Jaime Eduardo Cecilio Hallak1, José Alexandre de Sousa Crippa, Joel Porfírio Pinto, João Paulo Machado de Sousa, Clarissa Trzesniak, Serdar Murat Dursun, Phillip McGuire, John Francis William Deakin, Antonio Waldo Zuardi.   

Abstract

The hypothesis that schizophrenia involves aberrant inter-hemispheric communication has a long pedigree, however its precise role remains unclear. We therefore report the case of a total agenesis of the corpus callosum in a 21-year-old man with childhood-onset schizophrenia. The presence of schizophrenia with very early onset on absence of corpus callosum offers an opportunity to examine neurodevelopmental model and theories regarding to interhemispheric communication in the pathogenesis of psychosis.

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Year:  2007        PMID: 18345433     DOI: 10.1590/s0004-282x2007000700024

Source DB:  PubMed          Journal:  Arq Neuropsiquiatr        ISSN: 0004-282X            Impact factor:   1.420


  2 in total

1.  Genetic and functional analyses identify DISC1 as a novel callosal agenesis candidate gene.

Authors:  Nathan Osbun; Jiang Li; Mary C O'Driscoll; Zoe Strominger; Mari Wakahiro; Eric Rider; Polina Bukshpun; Elena Boland; Cailyn H Spurrell; Wendy Schackwitz; Len A Pennacchio; William B Dobyns; Graeme C M Black; Elliott H Sherr
Journal:  Am J Med Genet A       Date:  2011-07-07       Impact factor: 2.802

2.  Agenesis of corpus callosum and emotional information processing in schizophrenia.

Authors:  Ovidiu Lungu; Emmanuel Stip
Journal:  Front Psychiatry       Date:  2012-02-03       Impact factor: 4.157

  2 in total

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