Literature DB >> 18344953

Anatomical and visual outcome after vitrectomy with triamcinolone acedonide-assisted epiretinal membrane removal in highly myopic eyes with retinal detachment due to macular hole.

X Fang1, X Zheng, Y Weng, Z Chen, J Liu, B Chen, P Wu, H Ni, K Yao.   

Abstract

PURPOSE: To determine the effectiveness of staining an epiretinal membrane (ERM) with triamicinolone acedonide (TA) during vitrectomy for a retinal detachment (RD) due to a macular hole (MH) in highly myopic eyes. PATIENTS AND METHODS: Thirty-four highly myopic eyes (>-6.0 dioptres) of 34 patients with an RD caused by an MH underwent vitrectomy with TA-assisted ERM removal. The excised ERMs from five eyes were examined by transmission electron microscopy (TEM). The main outcome measures were the retinal status and best-corrected visual acuity (BCVA). The anatomic status of the MH was determined by optic coherence tomography (OCT) in 24 successfully retinal-reattached eyes. The follow-up periods ranged from 5 to 20 months.
RESULTS: The granules of TA adhered to the ERM and the residual posterior hyaloid, which made them more visible and facilitated their removal. Tissues resembling the internal limiting membrane were not detected in any of the five excised tissues. The retinal reattachment rate was 88% after the first surgery. The mean log MAR BCVA significantly improved from 1.83+/-0.50 (mean+/-SD) before surgery to 1.22+/-0.35 at the final follow-up (P<0.001, Wilcoxon signed rank test). OCT showed a normal concave appearance in 11 of 24 eyes (46%), but a central neural epithelial defect was present in 13 of 24 eyes (54%).
CONCLUSIONS: TA facilitates the complete removal of both the ERM and residual posterior hyaloid, thus ensuring high anatomical and visual success rates in highly myopic eyes with an RD due to MH.

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Year:  2008        PMID: 18344953     DOI: 10.1038/eye.2008.60

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  4 in total

1.  Vitreo-retinal relationship and post-operative outcome of macular hole repair in eyes with high myopia.

Authors:  Li-Li Wu; Tzyy-Chang Ho; Chang-Hao Yang; Chung-May Yang
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2015-03-28       Impact factor: 3.117

2.  Late recurrence of myopic foveoschisis after successful repair with primary vitrectomy and incomplete membrane peeling.

Authors:  Gonzalo Sepúlveda; Stanley Chang; K Bailey Freund; SungPyo Park; Quan V Hoang
Journal:  Retina       Date:  2014-09       Impact factor: 4.256

Review 3.  Retinal Changes Induced by Epiretinal Tangential Forces.

Authors:  Mario R Romano; Chiara Comune; Mariantonia Ferrara; Gilda Cennamo; Stefano De Cillà; Lisa Toto; Giovanni Cennamo
Journal:  J Ophthalmol       Date:  2015-09-03       Impact factor: 1.909

4.  Inverted internal limiting membrane flap technique for retinal detachment due to macular holes in high myopia with axial length ≥ 30 mm.

Authors:  Changzhong Xu; Chao Feng; Mengyao Han; Junwen He; Rui Zhang; Tao Yan; Xiangyun Li; Yong Liu; Yanzi Li; Jianhua Wu
Journal:  Sci Rep       Date:  2022-03-11       Impact factor: 4.379

  4 in total

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