Literature DB >> 18344245

Continuous deep sedation for patients nearing death in the Netherlands: descriptive study.

Judith Rietjens1, Johannes van Delden, Bregje Onwuteaka-Philipsen, Hilde Buiting, Paul van der Maas, Agnes van der Heide.   

Abstract

OBJECTIVES: To study the practice of continuous deep sedation in 2005 in the Netherlands and compare it with findings from 2001.
DESIGN: Questionnaire study about random samples of deaths reported to a central death registry in 2005 and 2001.
SETTING: Nationwide physician study in the Netherlands. PARTICIPANTS: Reporting physicians received a questionnaire about the medical decisions that preceded the patient's death; 78% (n=6860) responded in 2005 and 74% (n=5617) in 2001. MAIN OUTCOME MEASURES: Characteristics of continuous deep sedation (attending physician, types of patients, drugs used, duration, estimated effect on shortening life, palliative consultation). Requests for euthanasia.
RESULTS: The use of continuous deep sedation increased from 5.6% (95% confidence interval 5.0% to 6.2%) of deaths in 2001 to 7.1% (6.5% to 7.6%) in 2005, mostly in patients treated by general practitioners and in those with cancer (in 2005, 47% of sedated patients had cancer v 33% in 2001). In 83% of cases sedation was induced by benzodiazepines, and in 94% patients were sedated for periods of less than one week until death. Nine per cent of those who received continuous deep sedation had previously requested euthanasia but their requests were not granted. Nine per cent of the physicians had consulted a palliative expert.
CONCLUSIONS: The increased use of continuous deep sedation for patients nearing death in the Netherlands and the limited use of palliative consultation suggests that this practice is increasingly considered as part of regular medical practice.

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Year:  2008        PMID: 18344245      PMCID: PMC2292332          DOI: 10.1136/bmj.39504.531505.25

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  26 in total

Review 1.  Existential suffering and palliative sedation: a brief commentary with a proposal for clinical guidelines.

Authors:  P Rousseau
Journal:  Am J Hosp Palliat Care       Date:  2001 May-Jun       Impact factor: 2.500

2.  Terminal sedation: an acceptable exit strategy?

Authors:  Muriel R Gillick
Journal:  Ann Intern Med       Date:  2004-08-03       Impact factor: 25.391

3.  Sedation and expertise in palliative care.

Authors:  José António Ferraz Gonçalves
Journal:  J Clin Oncol       Date:  2006-09-01       Impact factor: 44.544

4.  Improving prescription in palliative sedation: compliance with dutch guidelines.

Authors:  Jeroen G J Hasselaar; Rob P B Reuzel; Stans C A H H V M Verhagen; Alexander de Graeff; Kris C P Vissers; Ben J P Crul
Journal:  Arch Intern Med       Date:  2007-06-11

5.  Palliative options of last resort: a comparison of voluntarily stopping eating and drinking, terminal sedation, physician-assisted suicide, and voluntary active euthanasia.

Authors:  T E Quill; B Lo; D W Brock
Journal:  JAMA       Date:  1997-12-17       Impact factor: 56.272

6.  Terminal sedation and euthanasia: a comparison of clinical practices.

Authors:  Judith A C Rietjens; Johannes J M van Delden; Agnes van der Heide; Astrid M Vrakking; Bregje D Onwuteaka-Philipsen; Paul J van der Maas; Gerrit van der Wal
Journal:  Arch Intern Med       Date:  2006-04-10

Review 7.  Palliative sedation therapy in the last weeks of life: a literature review and recommendations for standards.

Authors:  Alexander de Graeff; Mervyn Dean
Journal:  J Palliat Med       Date:  2007-02       Impact factor: 2.947

8.  Physician reports of terminal sedation without hydration or nutrition for patients nearing death in the Netherlands.

Authors:  Judith A C Rietjens; Agnes van der Heide; Astrid M Vrakking; Bregje D Onwuteaka-Philipsen; Paul J van der Maas; Gerrit van der Wal
Journal:  Ann Intern Med       Date:  2004-08-03       Impact factor: 25.391

9.  Symptom burden in the last week of life.

Authors:  Marianne Klinkenberg; Dick L Willems; Gerrit van der Wal; Dorly J H Deeg
Journal:  J Pain Symptom Manage       Date:  2004-01       Impact factor: 3.612

10.  Sedation in palliative care - a critical analysis of 7 years experience.

Authors:  H Christof Muller-Busch; Inge Andres; Thomas Jehser
Journal:  BMC Palliat Care       Date:  2003-05-13       Impact factor: 3.234

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  27 in total

1.  Continuous deep sedation in patients nearing death.

Authors:  Scott A Murray; Kirsty Boyd; Ira Byock
Journal:  BMJ       Date:  2008-03-14

2.  [Finding the right words for medical decisions at life's end].

Authors:  Jürgen Wallner
Journal:  Wien Klin Wochenschr       Date:  2008       Impact factor: 1.704

3.  Consultation with specialist palliative care services in palliative sedation: considerations of Dutch physicians.

Authors:  Ian Koper; Agnes van der Heide; Rien Janssens; Siebe Swart; Roberto Perez; Judith Rietjens
Journal:  Support Care Cancer       Date:  2013-09-14       Impact factor: 3.603

4.  Continuous deep sedation: Dutch research reflects problems with the Liverpool care pathway.

Authors:  Adrian J Treloar
Journal:  BMJ       Date:  2008-04-26

5.  Euthanasia and physician-assisted suicide in amyotrophic lateral sclerosis: a prospective study.

Authors:  Maud Maessen; Jan H Veldink; Bregje D Onwuteaka-Philipsen; Henk T Hendricks; Helenius J Schelhaas; Hepke F Grupstra; Gerrit van der Wal; Leonard H van den Berg
Journal:  J Neurol       Date:  2014-07-15       Impact factor: 4.849

6.  Attitudes of palliative home care physicians towards palliative sedation at home in Italy.

Authors:  Sebastiano Mercadante; Francesco Masedu; Alessandro Mercadante; Franco Marinangeli; Federica Aielli
Journal:  Support Care Cancer       Date:  2017-01-17       Impact factor: 3.603

7.  Continuous sedation until death: moral justifications of physicians and nurses--a content analysis of opinion pieces.

Authors:  Sam Rys; Freddy Mortier; Luc Deliens; Reginald Deschepper; Margaret Pabst Battin; Johan Bilsen
Journal:  Med Health Care Philos       Date:  2013-08

8.  Making sense of continuous sedation in end-of-life care for cancer patients: an interview study with bereaved relatives in three European countries.

Authors:  S M Bruinsma; J Brown; A van der Heide; L Deliens; L Anquinet; S A Payne; J E Seymour; J A C Rietjens
Journal:  Support Care Cancer       Date:  2014-07-15       Impact factor: 3.603

9.  Requests for euthanasia in general practice before and after implementation of the Dutch Euthanasia Act.

Authors:  Jojanneke E van Alphen; Gé A Donker; Richard L Marquet
Journal:  Br J Gen Pract       Date:  2010-04       Impact factor: 5.386

10.  Two Decades of Research on Euthanasia from the Netherlands. What Have We Learnt and What Questions Remain?

Authors:  Judith A C Rietjens; Paul J van der Maas; Bregje D Onwuteaka-Philipsen; Johannes J M van Delden; Agnes van der Heide
Journal:  J Bioeth Inq       Date:  2009-07-28       Impact factor: 1.352

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