| Literature DB >> 18343886 |
John W Cain1, David G Schaeffer.
Abstract
It is known, from both experiments and simulations, that cardiac action potentials are shortened near a non-conducting boundary. In the present paper, this effect is studied in a simple, two-current ionic model, with propagation restricted to a 1D fibre. An asymptotic approximation for the dependence of action potential duration on distance to the boundary is derived. This estimate agrees well with simulations.Mesh:
Year: 2008 PMID: 18343886 PMCID: PMC2447675 DOI: 10.1093/imammb/dqn002
Source DB: PubMed Journal: Math Med Biol ISSN: 1477-8599 Impact factor: 1.854