OBJECTIVE: To describe the spontaneous evolution of tibial somatosensory evoked potentials (tSSEPs) after spinal cord injury (SCI) and its relation to neurological and functional parameters. METHODS: tSSEPs were assessed in 297 patients within five standardized time intervals throughout the first year after injury, along with neurological and functional parameters. RESULTS: Roughly 60% of the patients did not show any recordable tSSEP throughout the first year after injury. Approximately 20% had recordable potentials at every assessment stage and showed an improvement of tSSEP parameters over time. In about 10% of the patients, a potential recovered during the first year. In the remaining cases, potentials were inconsistently recordable. All groups showed a similar amount of neurological and functional improvement. CONCLUSIONS: Recordability, latencies and amplitudes of tSSEPs can change over time after SCI. The early recordability of a tSSEP is associated with a favorable functional and neurological status and outcome. In contrast, an initially absent tSSEP is not always associated with a poorer status and outcome but only in those 75% of the patients in whom the potential remains absent. SIGNIFICANCE: This exact description of the spontaneous improvements of neurophysiological, neurological and functional parameters after SCI is an important prerequisite in appraising the efficacy of new interventional therapies.
OBJECTIVE: To describe the spontaneous evolution of tibial somatosensory evoked potentials (tSSEPs) after spinal cord injury (SCI) and its relation to neurological and functional parameters. METHODS: tSSEPs were assessed in 297 patients within five standardized time intervals throughout the first year after injury, along with neurological and functional parameters. RESULTS: Roughly 60% of the patients did not show any recordable tSSEP throughout the first year after injury. Approximately 20% had recordable potentials at every assessment stage and showed an improvement of tSSEP parameters over time. In about 10% of the patients, a potential recovered during the first year. In the remaining cases, potentials were inconsistently recordable. All groups showed a similar amount of neurological and functional improvement. CONCLUSIONS: Recordability, latencies and amplitudes of tSSEPs can change over time after SCI. The early recordability of a tSSEP is associated with a favorable functional and neurological status and outcome. In contrast, an initially absent tSSEP is not always associated with a poorer status and outcome but only in those 75% of the patients in whom the potential remains absent. SIGNIFICANCE: This exact description of the spontaneous improvements of neurophysiological, neurological and functional parameters after SCI is an important prerequisite in appraising the efficacy of new interventional therapies.
Authors: Michèle Hubli; John L K Kramer; Catherine R Jutzeler; Jan Rosner; Julio C Furlan; Keith E Tansey; Martin Schubert Journal: Spinal Cord Date: 2019-07-23 Impact factor: 2.772
Authors: Jason C Eck; Christopher J Martin; Anthony Lapinsky; Patrick J Connolly; Christian Dipaola Journal: J Clin Monit Comput Date: 2012-09-02 Impact factor: 2.502
Authors: Marcel Simis; Deniz Doruk Camsari; Marta Imamura; Thais Raquel Martins Filippo; Daniel Rubio De Souza; Linamara Rizzo Battistella; Felipe Fregni Journal: Front Hum Neurosci Date: 2021-04-09 Impact factor: 3.169
Authors: Soshi Samejima; Charlotte D Caskey; Fatma Inanici; Siddhi R Shrivastav; Lorie N Brighton; Jared Pradarelli; Vincente Martinez; Katherine M Steele; Rajiv Saigal; Chet T Moritz Journal: Phys Ther Date: 2022-01-01