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Literature DB >> 18343119

Non-steroidal anti-inflammatory drug use and the risk of Parkinson disease: a retrospective cohort study.

Mahyar Etminan¹, Bruce C Carleton, Ali Samii.

Abstract

Using the British Columbia Linked Health Databases, we explored the association between nonsteroidal anti-inflammatory drugs (NSAIDs) and the risk of developing Parkinson's disease (PD). We followed a cohort of older adults in the Province of British Columbia from 1997 to 2003. A time-dependent Cox model was used to estimate adjusted rate ratios for users and non-users of NSAIDs. The results of our study did not show a protective effect of NSAIDs for PD (rate ratio 0.84, 95% CI 0.81-1.09).

Entities: Disease

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Year: 2008 PMID： 18343119 DOI： 10.1016/j.jocn.2007.02.095

Source DB: PubMed Journal: J Clin Neurosci ISSN： 0967-5868 Impact factor: 1.961

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Cited

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Non-steroidal anti-inflammatory drug use and the risk of Parkinson disease: a retrospective cohort study.

1. Risk for Parkinson's disease among patients with osteoarthritis: a Danish cohort study.

Review 2. The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research.

Review 3. Microglial phenotype and adaptation.

4. Polymer brain-nanotherapeutics for multipronged inhibition of microglial α-synuclein aggregation, activation, and neurotoxicity.

5. Use of ibuprofen and risk of Parkinson disease.

6. Systemic LPS administration induces brain inflammation but not dopaminergic neuronal death in the substantia nigra.

7. Autoimmune disease and risk for Parkinson disease: a population-based case-control study.

8. Diverse methyl sulfone-containing benzo[b]thiophene library via iodocyclization and palladium-catalyzed coupling.

9. Cyclooxygenase and neuroinflammation in Parkinson's disease neurodegeneration.

Review 10. Neural and immune mechanisms in the pathogenesis of Parkinson's disease.