OBJECTIVES: To examine the contributions of fear of recurrence and the more commonly examined treatment-related symptoms to the health-related quality of life (HRQOL) of men treated for localized prostate cancer. METHODS: A total of 730 men with localized disease were identified from the Cancer of the Prostate Strategic Urologic Research Endeavor, a national, prospective study of men with prostate cancer. Pre- to post-treatment changes in fear of recurrence, treatment-specific symptoms and burden, comorbidities at diagnosis, number of new symptoms, and post-treatment HRQOL data were analyzed. RESULTS: Linear regression, adjusted for clinical and demographic characteristics, showed that improved fear of recurrence (P <0.01), higher number of post-treatment symptoms (P <0.01), and improved bowel function (P <0.01) significantly predicted better mental health scores. For physical health, improved urinary bother (P <0.01) and lower number of post-treatment symptoms (P <0.01) were associated with better physical health. CONCLUSION: Understanding men's fears about cancer recurrence and how these fears influence physical and mental health are important components of providing care to this growing population.
OBJECTIVES: To examine the contributions of fear of recurrence and the more commonly examined treatment-related symptoms to the health-related quality of life (HRQOL) of men treated for localized prostate cancer. METHODS: A total of 730 men with localized disease were identified from the Cancer of the Prostate Strategic Urologic Research Endeavor, a national, prospective study of men with prostate cancer. Pre- to post-treatment changes in fear of recurrence, treatment-specific symptoms and burden, comorbidities at diagnosis, number of new symptoms, and post-treatment HRQOL data were analyzed. RESULTS: Linear regression, adjusted for clinical and demographic characteristics, showed that improved fear of recurrence (P <0.01), higher number of post-treatment symptoms (P <0.01), and improved bowel function (P <0.01) significantly predicted better mental health scores. For physical health, improved urinary bother (P <0.01) and lower number of post-treatment symptoms (P <0.01) were associated with better physical health. CONCLUSION: Understanding men's fears about cancer recurrence and how these fears influence physical and mental health are important components of providing care to this growing population.
Authors: Youngmee Kim; Charles S Carver; Rachel L Spillers; Melissa Love-Ghaffari; Chiew-Kwei Kaw Journal: Qual Life Res Date: 2011-06-21 Impact factor: 4.147
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Authors: Teletia R Taylor; Edward D Huntley; Jennifer Sween; Kepher Makambi; Thomas A Mellman; Carla D Williams; Pamela Carter-Nolan; Wayne Frederick Journal: Int J Behav Med Date: 2012-09
Authors: Steven B Zeliadt; Scott D Ramsey; Arnold L Potosky; Neeraj K Arora; David K Blough; Ingrid Oakley-Girvan; Ann S Hamilton; Stephen K Van Den Eeden; David F Penson Journal: Patient Date: 2008-07-01 Impact factor: 3.883