Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Increased mTORC1 signaling UPRegulates stress.

Literature DB >> 18342598

Increased mTORC1 signaling UPRegulates stress.

Abstract

In this issue of Molecular Cell, Ozcan et al. (2008) show that the loss of the tuberous sclerosis tumor suppressor complex induces endoplasmic reticulum stress, leading to attenuation of insulin receptor signaling activity via the unfolded protein response.

Entities: Disease Gene

Mesh：

Substances：

Year: 2008 PMID： 18342598 DOI： 10.1016/j.molcel.2008.02.011

Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970

Keyword Cloud
Cited

10 in total

Review 1. PI3 Kinase regulation of neural regeneration and muscle hypertrophy after spinal cord injury.

Authors: Tengfei Zhao; Yiying Qi; Yan Li; Kan Xu
Journal: Mol Biol Rep Date: 2011-07-01 Impact factor: 2.316

2. Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.

Authors: Bo-Jhih Guan; Dawid Krokowski; Mithu Majumder; Christine L Schmotzer; Scot R Kimball; William C Merrick; Antonis E Koromilas; Maria Hatzoglou
Journal: J Biol Chem Date: 2014-03-19 Impact factor: 5.157

3. Mtl1 is required to activate general stress response through Tor1 and Ras2 inhibition under conditions of glucose starvation and oxidative stress.

Authors: Mima Ivanova Petkova; Nuria Pujol-Carrion; Javier Arroyo; Jesús García-Cantalejo; Maria Angeles de la Torre-Ruiz
Journal: J Biol Chem Date: 2010-04-13 Impact factor: 5.157

4. The Human FSGS-Causing ANLN R431C Mutation Induces Dysregulated PI3K/AKT/mTOR/Rac1 Signaling in Podocytes.

Authors: Gentzon Hall; Brandon M Lane; Kamal Khan; Igor Pediaditakis; Jianqiu Xiao; Guanghong Wu; Liming Wang; Maria E Kovalik; Megan Chryst-Stangl; Erica E Davis; Robert F Spurney; Rasheed A Gbadegesin
Journal: J Am Soc Nephrol Date: 2018-07-12 Impact factor: 10.121

Increased mTORC1 signaling UPRegulates stress.

Review 1. PI3 Kinase regulation of neural regeneration and muscle hypertrophy after spinal cord injury.

2. Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.

3. Mtl1 is required to activate general stress response through Tor1 and Ras2 inhibition under conditions of glucose starvation and oxidative stress.

4. The Human FSGS-Causing ANLN R431C Mutation Induces Dysregulated PI3K/AKT/mTOR/Rac1 Signaling in Podocytes.

Review 5. The pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitus.

Review 6. mTOR-dependent signalling in Alzheimer's disease.

7. Rasfonin promotes autophagy and apoptosis via upregulation of reactive oxygen species (ROS)/JNK pathway.

8. ATG5 and ATG7 induced autophagy interplays with UPR via PERK signaling.

9. Citrus Peel Extract Ameliorates High-Fat Diet-Induced NAFLD via Activation of AMPK Signaling.

Review 10. Milk--A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent Translation.