S Toovey1. 1. SAA-Netcare Travel Clinics, Johannesburg, South Africa. malaria@freesurf.ch
Abstract
OBJECTIVES: To assess artemether-lumefantrine effectiveness in the treatment of falciparum malaria in an unsupervised outpatient setting in Africa. DESIGN: Open label prospective study. SETTING: Occupational health clinic, Mozambique. SUBJECTS: Semi-immune Mozambican adults. OUTCOME MEASURES: 28-day treatment failures. RESULTS: 54/54 subjects were smear negative on day 2, and at 'day 28' (range 26-34 days). CONCLUSIONS: Artemether-lumefantrine is effective in semi-immune adults in an unsupervised outpatient setting in Southern Africa, with no evidence of recrudescence.
OBJECTIVES: To assess artemether-lumefantrine effectiveness in the treatment of falciparum malaria in an unsupervised outpatient setting in Africa. DESIGN: Open label prospective study. SETTING: Occupational health clinic, Mozambique. SUBJECTS: Semi-immune Mozambican adults. OUTCOME MEASURES: 28-day treatment failures. RESULTS: 54/54 subjects were smear negative on day 2, and at 'day 28' (range 26-34 days). CONCLUSIONS:Artemether-lumefantrine is effective in semi-immune adults in an unsupervised outpatient setting in Southern Africa, with no evidence of recrudescence.